CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020424
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cAMP-dependent protein kinase inhibitor beta 
Protein Synonyms/Alias
 PKI-beta 
Gene Name
 PKIB 
Gene Synonyms/Alias
 PRKACN2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48GTSDLPLKLEALSVKubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Protein kinase inhibitor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 78 AA 
Protein Sequence
MRTDSSKMTD VESGVANFAS SARAGRRNAL PDIQSSAATD GTSDLPLKLE ALSVKEDAKE 60
KDEKTTQDQL EKPQNEEK 78 
Gene Ontology
 GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IEA:InterPro. 
Interpro
 IPR004171; cAMP_dep_PKI. 
Pfam
 PF02827; PKI 
SMART
  
PROSITE
  
PRINTS