CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036761
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 60S ribosomal protein L26-like 1 
Protein Synonyms/Alias
  
Gene Name
 RPL26L1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51VRSMPIRKDDEVQVVacetylation[1]
51VRSMPIRKDDEVQVVubiquitination[2, 3, 4]
63QVVRGHYKGQQIGKVubiquitination[2]
69YKGQQIGKVVQVYRKacetylation[1]
69YKGQQIGKVVQVYRKubiquitination[2, 3, 4, 5, 6]
76KVVQVYRKKYVIYIEubiquitination[3]
77VVQVYRKKYVIYIERacetylation[4, 7]
77VVQVYRKKYVIYIERubiquitination[3, 5]
89IERVQREKANGTTVHubiquitination[3, 4]
103HVGIHPSKVVITRLKubiquitination[2, 3, 4, 5, 6]
113ITRLKLDKDRKKILEubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [6] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [7] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 128 AA 
Protein Sequence
MKFNPFVTSD RSKNRKRHFN APSHVRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG 60
HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSKVVITRLK LDKDRKKILE 120
RKAKSRQV 128 
Gene Ontology
 GO:0015934; C:large ribosomal subunit; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR005824; KOW.
 IPR014722; Rib_L2_dom2.
 IPR005825; Ribosomal_L24/26_CS.
 IPR005756; Ribosomal_L26/L24P_euk/arc.
 IPR008991; Translation_prot_SH3-like. 
Pfam
 PF00467; KOW 
SMART
 SM00739; KOW 
PROSITE
 PS01108; RIBOSOMAL_L24 
PRINTS