CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028840
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ras suppressor protein 1 
Protein Synonyms/Alias
 Ras suppressor protein 1, isoform CRA_a 
Gene Name
 Rsu1 
Gene Synonyms/Alias
 mCG_15700 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
72ISSLQKLKHLNLGMNacetylation[1, 2]
72ISSLQKLKHLNLGMNubiquitination[3]
141PDIGKLTKLQILSLRubiquitination[3]
166IGELTQLKELHIQGNacetylation[1]
226YIRSETYKYLYGRHMubiquitination[3]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 260 AA 
Protein Sequence
MSKSLKKLVE ESREKNQPEV DMSDRGISSM LDVNGLSVPP NVAELKNLEV LNFFNNQIEE 60
LPTQISSLQK LKHLNLGMNR LNTLPRGFGS LPALEVLDLT YNNLNEHSLP GNFFYLTTLR 120
ALYLSDNDFE ILPPDIGKLT KLQILSLRDN DLISLPKEIG ELTQLKELHI QGNRLTVLPP 180
ELGNLDLTGQ KQVFKAENNP WVTPIADQFQ LGVSHVFEYI RSETYKYLYG RHMQANPEPP 240
KKNNDKSKKI SRKPLAAKNK 260 
Gene Ontology
 GO:0007265; P:Ras protein signal transduction; IMP:MGI. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003591; Leu-rich_rpt_typical-subtyp. 
Pfam
 PF00560; LRR_1
 PF12799; LRR_4 
SMART
 SM00369; LRR_TYP 
PROSITE
 PS51450; LRR 
PRINTS