CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029877
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Receptor tyrosine kinase-like orphan receptor 2, isoform CRA_b 
Protein Synonyms/Alias
 Tyrosine-protein kinase transmembrane receptor ROR2 
Gene Name
 ROR2 
Gene Synonyms/Alias
 hCG_1985325 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
349DRFGKVYKGHLFGPAubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Kinase; Kringle; Receptor; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 704 AA 
Protein Sequence
MKTITATGVL FVRLGPTHSP NHNFQDDYHE DGFCQPYRGI ACARFIGNRT IYVDSLQMQG 60
EIENRITAAF TMIGTSTHLS DQCSQFAIPS FCHFVFPLCD ARSRTPKPRE LCRDECEVLE 120
SDLCRQEYTI ARSNPLILMR LQLPKCEALP MPESPDAANC MRIGIPAERL GRYHQCYNGS 180
GMDYRGTAST TKSGHQCQPW ALQHPHSHHL SSTDFPELGG GHAYCRNPGG QMEGPWCFTQ 240
NKNVRMELCD VPSCSPRDSS KMGILYILVP SIAIPLVIAC LFFLVCMCRN KQKASASTPQ 300
RRQLMASPSQ DMEMPLINQH KQAKLKEISL SAVRFMEELG EDRFGKVYKG HLFGPAPGEQ 360
TQAVAIKTLK DKAEGPLREE FRHEAMLRAR LQHPNVVCLL GVVTKDQPLS MIFSYCSHGD 420
LHEFLVMRSP HSDVGSTDDD RTVKSALEPP DFVHLVAQIA AGMEYLSSHH VVHKDLATRN 480
VLVYDKLNVK ISDLGLFREV YAADYYKLLG NSLLPIRWMA PEAIMYGKFS IDSDIWSYGV 540
VLWEVFSYGL QPYCGYSNQD VVEMIRNRQV LPCPDDCPAW VYALMIECWN EFPSRRPRFK 600
DIHSRLRAWG NLSNYNSSAQ TSGASNTTQT SSLSTSPVSN VVRMRGSGRQ CWMTETPNAL 660
LWHNVSGVGS CRWVRGLADF KDEATDFRVM PRDPSLHCHV TSTA 704 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. 
Interpro
 IPR020067; Frizzled_dom.
 IPR011009; Kinase-like_dom.
 IPR000001; Kringle.
 IPR013806; Kringle-like.
 IPR018056; Kringle_CS.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
 IPR008266; Tyr_kinase_AS.
 IPR020635; Tyr_kinase_cat_dom. 
Pfam
 PF01392; Fz
 PF00051; Kringle
 PF07714; Pkinase_Tyr 
SMART
 SM00130; KR
 SM00219; TyrKc 
PROSITE
 PS50038; FZ
 PS00021; KRINGLE_1
 PS50070; KRINGLE_2
 PS50011; PROTEIN_KINASE_DOM
 PS00109; PROTEIN_KINASE_TYR 
PRINTS
 PR00109; TYRKINASE.