CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023777
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 28S ribosomal protein S23, mitochondrial 
Protein Synonyms/Alias
 MRP-S23; S23mt 
Gene Name
 MRPS23 
Gene Synonyms/Alias
 CGI-138; HSPC329 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
57RVRYGKAKAPIQDIWubiquitination[1, 2]
73HEDRIRAKFYSVYGSubiquitination[3]
93DLFNPNFKSTCQRFVubiquitination[3]
102TCQRFVEKYTELQKLacetylation[4]
108EKYTELQKLGETDEEubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 
Functional Description
  
Sequence Annotation
 MOD_RES 102 102 N6-acetyllysine.  
Keyword
 Acetylation; Complete proteome; Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 190 AA 
Protein Sequence
MAGSRLETVG SIFSRTRDLV RAGVLKEKPL WFDVYDAFPP LREPVFQRPR VRYGKAKAPI 60
QDIWYHEDRI RAKFYSVYGS GQRAFDLFNP NFKSTCQRFV EKYTELQKLG ETDEEKLFVE 120
TGKALLAEGV ILRRVGEART QHGGSHVSRK SEHLSVRPQT ALEENETQKE VPQDQHLEAP 180
ADQSKGLLPP 190 
Gene Ontology
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR023611; Ribosomal_S23/S25_mit.
 IPR019520; Ribosomal_S23_mit. 
Pfam
 PF10484; MRP-S23 
SMART
  
PROSITE
  
PRINTS