| Tag | Content |
|---|
| CPLM ID | CPLM-004828 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dolichol kinase |
Protein Synonyms/Alias | |
Gene Name | SEC59 |
Gene Synonyms/Alias | YMR013C; YM8270.17C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 18 | TTIKLTQKTEGSQMP | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. It is required for spore germination. Has an essential role in cellular metabolism. |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Kinase; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 519 AA |
Protein Sequence | MVAIIPHASF TTIKLTQKTE GSQMPTEEIC KINMRTRKFD VGGNSRDFEC FYSNFVQTVI 60
LLGTFFYCVE RLQPWSIVTA DISYKQIFVN VFVVCLIMVG LIFTKYWQHG YKSLPKFDTI 120
YSLYLPFMVS LLFDTSSTVI NTILILSVLN SYRWRTQLVV IILQLCLIFF NFEAGDRLKN 180
IISIVINSLL SLILKYIGQL KSLDNIDSNL FSILLTNILY VSEAGTVHFR ILKGIILALT 240
TIISINYVLK KVMHFKPFML SISFAIGLPL FANTFIHLED GENPLLWLVK YILESTIRQK 300
ILFAWSSILI LSIPSILIEK DSLSLNTSRK LWHFIIFLLI IPSFQMDSNF VKIALSGTIP 360
VFLSIEYIRF QNLPPLGSAI ELQLRRFADD RDHSGPLIIS YLYLLFGIST PLLMNNSPMG 420
LIGLGIGDSL ASIIGKRYGR IRWKGTQKTL EGTLAFIVTS FIVCLVLLRF DKAAIFNHLT 480
TLQLLTLCTL SGVLEGNSVL NDNILIPAFM MICEKLITL 519 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |