CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040085
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 WD repeat-containing protein 5 
Protein Synonyms/Alias
  
Gene Name
 Wdr5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
51IWDVSSGKCLKTLKGubiquitination[1]
90SVRIWDVKTGKCLKTubiquitination[1]
174VKFSPNGKYILAATLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 281 AA 
Protein Sequence
XIWGAYDGKF EKTISGHKLG ISDVAWSSDS NLLVSASDDK TLKIWDVSSG KCLKTLKGHS 60
NYVFCCNFNP QSNLIVSGSF DESVRIWDVK TGKCLKTLPA HSDPVSAVHF NRDGSLIVSS 120
SYDGLCRIWD TASGQCLKTL IVFVTSHEKR SPLRTPCDDD NPPVSFVKFS PNGKYILAAT 180
LDNTLKLWDY SKGKCLKTYT GHKNEKYCIF ANFSVTGGKW IVSGSEDNLV YIWNLQTKEI 240
VQKLQGHTDV VISTACHPTE NIIASAALEN DKTIKLWKSD C 281 
Gene Ontology
 GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:MGI.
 GO:0035097; C:histone methyltransferase complex; ISO:MGI.
 GO:0001501; P:skeletal system development; IDA:MGI. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.