| Tag | Content |
|---|
| CPLM ID | CPLM-021804 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Myozenin-1 |
Protein Synonyms/Alias | Calsarcin-2; Filamin-, actinin- and telethonin-binding protein; Protein FATZ |
Gene Name | Myoz1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 11 | SGTPAPNKRRKSSKL | ubiquitination | [1] | | 36 | SSGLNLGKKISVPRD | ubiquitination | [1] | | 69 | LRQMRVEKFIYENHP | ubiquitination | [1] | | 109 | GQGFSYGKGSSGGQA | ubiquitination | [1] | | 209 | DLLAYGAKAELPKYK | ubiquitination | [1] | | 230 | MPYGGYEKASKRMTF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
Sequence Annotation | |
Keyword | Cell projection; Complete proteome; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 296 AA |
Protein Sequence | MPLSGTPAPN KRRKSSKLIM ELTGGGRESS GLNLGKKISV PRDVMLEELS LLTNRGSKMF 60
KLRQMRVEKF IYENHPDVFS DSSMDHFQKF LPTVGGQLET AGQGFSYGKG SSGGQAGSSG 120
SAGQYGSDRH QQGSGFGAGG SGGPGGQAGG GGAPGTVGLG EPGSGDQAGG DGKHVTVFKT 180
YISPWDRAMG VDPQQKVELG IDLLAYGAKA ELPKYKSFNR TAMPYGGYEK ASKRMTFQMP 240
KFDLGPLLSE PLVLYNQNLS NRPSFNRTPI PWLSSGEHVD YNVDVGIPLD GETEEL 296 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |