UniProt Accession

 CANB1_MOUSE; Q63810; Q3V067; Q5F225 

Genbank Protein ID

 S43864; AK133403; AK145541; AK160938; AK163241; AL713926; AL606466; AL606466; AL713926 

Genbank Nucleotide ID

 AAB23171.1; BAE21637.1; BAE26495.1; BAE36102.1; BAE37251.1; CAI51912.1; CAI51912.1; CAI51920.1; CAI51920.1 

Protein Name

 Calcineurin subunit B type 1 

Protein Synonyms/Alias

 Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1 

Gene Name

 Ppp3r1 

Gene Synonyms/Alias

 Cnb 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
85	GVSQFSVKGDKEQKL	ubiquitination	[1]
125	MMVGNNLKDTQLQQI	ubiquitination	[1]
135	QLQQIVDKTIINADK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. 

Sequence Annotation

 DOMAIN 18 51 EF-hand 1.
 DOMAIN 50 85 EF-hand 2.
 DOMAIN 87 122 EF-hand 3.
 DOMAIN 128 163 EF-hand 4.
 MOD_RES 106 106 Phosphotyrosine.
 LIPID 2 2 N-myristoyl glycine (By similarity).  

Keyword

 Alternative splicing; Calcium; Complete proteome; Direct protein sequencing; Lipoprotein; Metal-binding; Myristate; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 170 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0042383; C:sarcolemma; IDA:BHF-UCL.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004721; F:phosphoprotein phosphatase activity; IMP:MGI.
 GO:0001837; P:epithelial to mesenchymal transition; IMP:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0060487; P:lung epithelial cell differentiation; IMP:MGI.
 GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.
 GO:0001569; P:patterning of blood vessels; IMP:MGI.
 GO:0006470; P:protein dephosphorylation; IMP:MGI. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF13499; EF_hand_5
 PF00036; efhand 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS