| Tag | Content |
|---|
| CPLM ID | CPLM-013922 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Unconventional myosin-XIX |
Protein Synonyms/Alias | Myosin head domain-containing protein 1 |
Gene Name | Myo19 |
Gene Synonyms/Alias | Myohd1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 830 | RMACLASKELDGMEE | ubiquitination | [1] | | 838 | ELDGMEEKPMPQAPG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility (By similarity). |
Sequence Annotation | DOMAIN 37 672 Myosin head-like.
DOMAIN 762 782 IQ 1.
DOMAIN 783 812 IQ 2.
REGION 829 963 Mitochondrial targeting. |
Keyword | Actin-binding; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Membrane; Mitochondrion; Mitochondrion outer membrane; Motor protein; Myosin; Nucleotide-binding; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 963 AA |
Protein Sequence | MLQQVNGHSL GSDAEGRASL KGDLREFLGG EIPLHQLDDL TKVNPVTLET VLRCLQARYT 60
EDIFYTNAGC TLVALNPFKH VPQLYAPELM QEYHAAPQPQ KLKPHIFTVG EQTYRNVKSL 120
IEPVNQSIVV SGESGAGKTW TSRCLMKFYA VVAASPTSCE NHKIAERIEQ RILNSNPVME 180
AFGNACTLRN SNSSRFGKFI QLQLNRAQQM TGAAVQTYLL EKTRVACQAS SERNFHIFYQ 240
ICKGATKDER LQWHLPEGTA FSWLPNPESS LEEDCFEVTR EAMLHLGIDT PTQNNIFKVL 300
AGLLHLGNVH FVDSEDEALP CQVMDDTKVS VRTSALLLQL PEKMLLESMQ IRTIKAGKQQ 360
QVFQKPCSRA ECDTRRDCLA KLIYARLFDW LVSVINSSIC ADSKSWTAFI GLLDVYGFES 420
FPNNSLEQLC INYANEKLQQ HFVAHYLRAQ QEEYEVEGLE WSFVNYQDNQ TCLDLLEGSP 480
ISICSLINEE CRLNRPSSAA QLQTRIESTL AGRPCLGHNK LSREPSFVVV HFAGPVRYHT 540
AGLVEKNKDP VPPELTELLQ QSQDPLLTML FPANPEEKTQ EELSGQSRAP ALTVVSKFKA 600
SLEQLLQVLH NTTPHYIRCI KPNSQSQPQT FLQEEVLNQL EACGLVETIH ISAAGFPIRV 660
SHQNFIERYK LLRRLGPRMS SGLGGLEPAE GSSEQPLCAK EATLQPLLQD ILHALPALIQ 720
TAATPSDPAK NTQIPLYCGR TKIFMTDSML ELLECGRAQM LEQCARCIQC GWRRHRLQKQ 780
EKQRRAAVLI QAAFRSWLTR KHIRRLHIAA TVIKHAWHKW RIRMACLASK ELDGMEEKPM 840
PQAPGTLRSS MSPAHTRFLG AIIHLWPLGL VLANSADGVR GFQRKLVAHA CLRLPSDRPS 900
NKVQTPQQDQ AGITSIRALP QGSIKFHCRK SPLQYADICP DPSASCVTGF NQILLESHRP 960
VQV 963 |
Gene Ontology | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. GO:0016459; C:myosin complex; IEA:UniProtKB-KW. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003774; F:motor activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |