| Tag | Content |
|---|
| CPLM ID | CPLM-017669 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 548 |
Protein Synonyms/Alias | |
Gene Name | ZNF548 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 154 | DWIPSFGKNHRVHMA | ubiquitination | [1] | | 272 | YECRECGKSFMYNYR | ubiquitination | [1] | | 338 | MDSSTLIKHQRVHTG | ubiquitination | [1] | | 394 | RYNSSLVKHWRNHTG | ubiquitination | [1] | | 440 | YECSECGKFFRYNSN | ubiquitination | [1] | | 450 | RYNSNLIKHWRNHTG | ubiquitination | [1] | | 473 | CGKAFSHKHILVEHQ | ubiquitination | [1] | | 542 | IRDFTMEKVYH**** | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 8 79 KRAB.
ZN_FING 197 219 C2H2-type 1.
ZN_FING 225 247 C2H2-type 2.
ZN_FING 253 275 C2H2-type 3.
ZN_FING 281 303 C2H2-type 4.
ZN_FING 309 331 C2H2-type 5.
ZN_FING 337 359 C2H2-type 6.
ZN_FING 365 387 C2H2-type 7.
ZN_FING 393 415 C2H2-type 8.
ZN_FING 421 443 C2H2-type 9.
ZN_FING 449 471 C2H2-type 10.
ZN_FING 477 499 C2H2-type 11. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 533 AA |
Protein Sequence | MNLTEGPLAM AEMDPTQGRV VFEDVAIYFS QEEWGHLDEA QRLLYRDVML ENLALLSSLG 60
SWHGAEDEEA PSQQGFSVGV SEVTASKPCL SSQKVHPSET CGPPLKDILC LVEHNGIHPE 120
QHIYICEAEL FQHPKQQIGE NLSRGDDWIP SFGKNHRVHM AEEIFTCMEG WKDLPATSCL 180
LQHQGPQSEW KPYRDTEDRE AFQTGQNDYK CSECGKTFTC SYSFVEHQKI HTGERSYECN 240
KCGKFFKYSA NFMKHQTVHT SERTYECREC GKSFMYNYRL MRHKRVHTGE RPYECNTCGK 300
FFRYSSTFVR HQRVHTGERP YECRECGKFF MDSSTLIKHQ RVHTGERPYK CNDCGKFFRY 360
ISTLIRHQRI HTGERPYECS VCGELFRYNS SLVKHWRNHT GERPYKCSEC GKSFRYHCRL 420
IRHQRVHTGE RPYECSECGK FFRYNSNLIK HWRNHTGERP YECRECGKAF SHKHILVEHQ 480
KIHSGERPYE CSECQKAFIR KSHLVHHQKI HSEERLVCSM NVGNSLAKTP TSLNIRDFTM 540
EKVYH 545 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |