CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007286
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SIP5 
Protein Synonyms/Alias
 SNF1-interacting protein 5 
Gene Name
 SIP5 
Gene Synonyms/Alias
 YMR140W; YM9375.09 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
33TSSNSVIKQYDEEASubiquitination[1]
64NGNNARTKTGSHLSSubiquitination[1]
237EMKRIGSKSSNVEDNubiquitination[1]
369PADSYVYKDAAISRAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 May negatively regulate the SNF1 kinase by promoting the interaction of the REG1/GLC7 phosphatase complex with the kinase. Deletion of SIP5 promotes resistance to artimisin, which is probably an indirect effect of an action on the electron transport chain. 
Sequence Annotation
 MOD_RES 13 13 Phosphoserine.
 MOD_RES 183 183 Phosphothreonine.
 MOD_RES 433 433 Phosphothreonine.
 MOD_RES 436 436 Phosphoserine.
 MOD_RES 438 438 Phosphothreonine.  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 489 AA 
Protein Sequence
MGNVPGKIDQ EDSFNDVRPD SSYNTTSSNS VIKQYDEEAS SRVRTRRTTS LVNNILNGNN 60
ARTKTGSHLS STSRRKTSRE KELAKEAHAK QLVVRCSETV DGGFLAPFGC YSFEKLDYDA 120
TVVKNLIIKR KLAPFYTPLQ DFDESWTRDE LIKIVDGLPL HDTFDENLEE FEDVPIGNLR 180
KSTFNELIDK SLSKKEQRRM HAKIFRARLY KKRILWQENE NETFLERKLE MKRIGSKSSN 240
VEDNTSSQPR KNYHLPSDDL KYTLYKNGSE CPICFLYFPG PFNYSKCCQQ PICTECFVQI 300
KRADPHFPHD EVDPTEPQTN DSEKDPNLLT SEPANCPYCA TASFSITYQP PTNRETGIGG 360
MPADSYVYKD AAISRADGGQ PNISAITSDT IRPDWEIKLN KERARLMRRS ANATAIHISN 420
RLIDPSHSRR RNTSHSITPI HDESTSASRS PEPTINELED QMVREAIRLS LEDQDNRKKS 480
KNRNTSLRP 489 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0042149; P:cellular response to glucose starvation; IMP:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS