UniProt Accession

 ATP8_RAT; P11608; Q35736 

Genbank Protein ID

 X14848; J01435 

Genbank Nucleotide ID

 CAA32958.1; AAD15018.1 

Protein Name

 ATP synthase protein 8 

Protein Synonyms/Alias

 A6L; Chargerin II; F-ATPase subunit 8 

Gene Name

 Mt-atp8 

Gene Synonyms/Alias

 Atp8; Atpase8; Mtatp8 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
54	TNNPWESKWTKIYLP	acetylation	[1]
57	PWESKWTKIYLPLSL	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity). 

Sequence Annotation

 MOD_RES 54 54 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; ATP synthesis; CF(0); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 67 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; IDA:UniProtKB.
 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
 GO:0055093; P:response to hyperoxia; IEP:RGD. 

Interpro

 IPR001421; ATPase_F0-cplx_su8_mt_metazoan. 

Pfam

 PF00895; ATP-synt_8 

SMART

  

PROSITE

  

PRINTS