CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041127
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-sensitive inward rectifier potassium channel 1 
Protein Synonyms/Alias
 Potassium inwardly-rectifying channel, subfamily J, member 1, isoform CRA_a 
Gene Name
 Kcnj1 
Gene Synonyms/Alias
 mCG_14022 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
332RFVPIVSKTKEGKYRubiquitination[1]
364AMCLYNEKDARARMKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 392 AA 
Protein Sequence
MDASDRRCMC RVLIRALTER MFKHLRRWFV THIFGRSRQR ARLVSKDGRC NIEFGNVDAQ 60
SRFIFFVDIW TTVLDLKWRY KMTVFITAFL GSWFLFGLLW YVVAYVHKDL PEFYPPDNRT 120
PCVENINGMT SAFLFSLETQ VTIGYGFRFV TEQCATAIFL LIFQSILGVI INSFMCGAIL 180
AKISRPKKRA KTITFSKNAV ISKRGGKLCL LIRVANLRKS LLIGSHIYGK LLKTTITPEG 240
ETIILDQTNI NFVVDAGNEN LFFISPLTIY HIIDHNSPFF HMAAETLSQQ DFELVVFLDG 300
TVESTSATCQ VRTSYIPEEV LWGYRFVPIV SKTKEGKYRV DFHNFGKTVE VETPHCAMCL 360
YNEKDARARM KRGYDNPNFV LSEVDETDDT QM 392 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
 GO:0072358; P:cardiovascular system development; IMP:MGI.
 GO:0001822; P:kidney development; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:1900128; P:regulation of G-protein activated inward rectifier potassium channel activity; IMP:MGI.
 GO:0070294; P:renal sodium ion absorption; IMP:MGI.
 GO:0001894; P:tissue homeostasis; IMP:MGI. 
Interpro
 IPR014756; Ig_E-set.
 IPR016449; K_chnl_inward-rec_Kir.
 IPR003268; K_chnl_inward-rec_Kir1.1.
 IPR013518; K_chnl_inward-rec_Kir_cyto. 
Pfam
 PF01007; IRK 
SMART
  
PROSITE
  
PRINTS
 PR01321; KIR11CHANNEL.
 PR01320; KIRCHANNEL.