CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myosin-IIIb 
Protein Synonyms/Alias
  
Gene Name
 MYO3B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
917PPHFSAGKAKVDTLEubiquitination[1]
1039SCVAILEKSRLDHWVubiquitination[2]
Reference
 [1] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1105 AA 
Protein Sequence
MLQSALLSTR KHLYGLFHYN PMMLGLESLP DPTDTWEIIE TIGKGTYGKV YKVTNKRDGS 60
LAAVKILDPV SDMDEEIEAE YNILQFLPNH PNVVKFYGMF YKADHCVGGQ LWLVLELCNG 120
GSVTELVKGL LRCGQRLDEA MISYILYGAL LGLQHLHNNR IIHRDVKGNN ILLTTEGGVK 180
LVDFGVSAQL TSTRLRRNTS VGTPFWMAPE VIACEQQYDS SYDARCDVWS LGITAIELGD 240
GDPPLFDMHP VKTLFKIPRN PPPTLLHPEK WCEEFNHFIS QCLIKDFERR PSVTHLLDHP 300
FIKGVHGKVL FLQKQLAKVL QDQKHQNPVA KTRHERMHTR RPYHVEDAEK YCLEDDLVNL 360
EVLDEDTIIH QLQKRYADLL IYTYVGDILI ALNPFQNLSI YSPQFSRLYH GVKRASNPPH 420
IFASADAAYQ CMVTLSKDQC IVISGESGSG KTESAHLIVQ HLTFLGKANN QTLREKILQV 480
NSLVEAFGNS CTAINDNSSR FGKYLEMMFT PTGVVMGARI SEYLLEKSRV IKQAAREKNF 540
HIFYYIYAGL HHQKKLSDFR LPEEKPPRYI ADETGRVMHD ITSKESYRRQ FEAIQHCFRI 600
IGFTDKEVHS VYRILAGILN IGNIEFAAIS SQHQTDKSEV PNAEALQNAA SVLCISPEEL 660
QEALTSHCVV TRGETIIRAN TVDRAADVRD AMSKALYGRL FSWIVNRINT LLQPDENICS 720
AGGGMNVGIL DIFGFENFQR NSFEQLCINI ANEQIQYYFN QHVFALEQME YQNEGIDAVP 780
VEYEDNRPLL DMFLQKPLGL LALLDEESRF PQATDQTLVD KFEDNLRCKY FWRPKGVELC 840
FGIQHYAGKV LYDASGVLEK NRDTLPADVV VVLRTSENKL LQQLFSIPLT KTGNLAQTRA 900
RITVASSSLP PHFSAGKAKV DTLEVIRHPE ETTNMKRQTV ASYFRYSLMD LLSKMVVGQP 960
HFVRCIKPND DREALQFSRE RVLAQLRSTG ILETVSIRRQ GYSHRILFEE FVKRYYYLAF 1020
TAHQTPLASK ESCVAILEKS RLDHWVLGKT KVFLKYYHVE QLNLLLREVI GRVVVLQAYT 1080
KGWLGARRYK RVREKREKGA IAIQS 1105 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR011009; Kinase-like_dom.
 IPR001609; Myosin_head_motor_dom.
 IPR027417; P-loop_NTPase.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00063; Myosin_head
 PF00069; Pkinase 
SMART
 SM00242; MYSc
 SM00220; S_TKc 
PROSITE
 PS50096; IQ
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS
 PR00193; MYOSINHEAVY.