CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042934
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ankyrin repeat domain-containing protein 13A 
Protein Synonyms/Alias
  
Gene Name
 ANKRD13A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49MEVNHDDKVVTTERFubiquitination[1, 2, 3]
71RLTLDLMKPKSREVEubiquitination[1, 2, 3, 4, 5, 6]
73TLDLMKPKSREVERRubiquitination[2, 3, 7]
93INTSLDTKNIAFERTubiquitination[1, 2, 3, 4, 5, 6, 7]
101NIAFERTKSGFWGWRubiquitination[6]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [5] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [6] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [7] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 302 AA 
Protein Sequence
XIWKSGAKLR VDITLLGFEN MSWIRGRRSF IFKGEDNWAE LMEVNHDDKV VTTERFDLSQ 60
EMERLTLDLM KPKSREVERR LTSPVINTSL DTKNIAFERT KSGFWGWRTD KAEVVNGYEA 120
KVYTVNNVNV ITKIRTEHLT EEEKKRYKDR NPLESLLGTV EHQFGAQGDL TTECATANNP 180
TAITPDEYFN EEFDLKDRDI GRPKELTIRT QKFKAMLWMC EEFPLSLVEQ VIPIIDLMAR 240
TSAHFARLRD FIKLEFPPGF PVKIEIPLFH VLNARITFGN VNGCSTAEES VSQNVEGTQA 300
DS 302 
Gene Ontology
  
Interpro
 IPR021832; ANKRD13. 
Pfam
 PF11904; GPCR_chapero_1 
SMART
  
PROSITE
  
PRINTS