CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017951
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SH3KBP1-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 SHKBP1 
Gene Synonyms/Alias
 PP203 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28IHLNVGGKRFSTSRQubiquitination[1]
181LGRMLDEKTPPSPSGubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
 DOMAIN 19 88 BTB.
 REPEAT 233 280 WD 1.
 REPEAT 283 322 WD 2.
 REPEAT 324 359 WD 3.
 REPEAT 428 466 WD 4.
 REPEAT 548 586 WD 5.
 MOD_RES 649 649 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 707 AA 
Protein Sequence
MAAAATAAEG VPSRGPPGEV IHLNVGGKRF STSRQTLTWI PDSFFSSLLS GRISTLKDET 60
GAIFIDRDPT VFAPILNFLR TKELDPRGVH GSSLLHEAQF YGLTPLVRRL QLREELDRSS 120
CGNVLFNGYL PPPVFPVKRR NRHSLVGPQQ LGGRPAPVRR SNTMPPNLGN AGLLGRMLDE 180
KTPPSPSGQP EEPGMVRLVC GHHNWIAVAY TQFLVCYRLK EASGWQLVFS SPRLDWPIER 240
LALTARVHGG ALGEHDKMVA AATGSEILLW ALQAEGGGSE IGAHRGVECR HQALAGPGGA 300
AHHQL 305 
Gene Ontology
 GO:0051260; P:protein homooligomerization; IEA:InterPro. 
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR003131; T1-type_BTB.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF02214; K_tetra 
SMART
 SM00225; BTB
 SM00320; WD40 
PROSITE
 PS50097; BTB
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS