CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025952
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinetochore-associated protein DSN1 homolog 
Protein Synonyms/Alias
  
Gene Name
 DSN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
165LHYQQEAKEILSRGSubiquitination[1]
176SRGSTEAKITEVKVEubiquitination[1, 2, 3]
181EAKITEVKVEPMTYLubiquitination[1]
199QNEVLNTKPDYQKILubiquitination[1, 2]
204NTKPDYQKILQNQSKubiquitination[2]
250KVSVQLGKRSMQQLDubiquitination[1]
266SPARKLLKLQLQNPPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MTSVTRSEII DEQSASYQDR RQSWRRASMK ETNRRKSLHP IHQGITELSR SISVDLAESK 60
RLGCLLLSSF QFSIQKLEPF LRDTKGFSLE SFRAKASSLS EELKHFADGL ETDGTLQKCF 120
EDSNGKASDF SLEASVAEMK EYITKFSLER QTWDQLLLHY QQEAKEILSR GSTEAKITEV 180
KVEPMTYLGS SQNEVLNTKP DYQKILQNQS KVFDCMELVM DELQGSVKQL QAFMDESTQC 240
FQKVSVQLGK RSMQQLDPSP ARKLLKLQLQ NPPAIHGSGS GSCQ 284 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR013218; Mtw1_DSN1. 
Pfam
 PF08202; Mis12_component 
SMART
  
PROSITE
  
PRINTS