CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042592
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutamate--cysteine ligase catalytic subunit 
Protein Synonyms/Alias
  
Gene Name
 GCLC 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
159VINVPIFKDKNTPSPubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 173 AA 
Protein Sequence
XETKRHADHV RRHGILQFLH IYHAVKDRHK DVLKWGDEVE YMLVSFDHEN KKVRLVLSGE 60
KVLETLQEKG ERTNPNHPTL WRPEYGSYMI EGTPGQPYGG TMSEFNTVEA NMRKRRKEAT 120
SILEENQALC TITSFPSTLT RNIRHRRGEK VVINVPIFKD KNTPSPFIET FTE 173 
Gene Ontology
 GO:0004357; F:glutamate-cysteine ligase activity; IEA:InterPro.
 GO:0006750; P:glutathione biosynthetic process; IEA:InterPro. 
Interpro
 IPR004308; GCS. 
Pfam
  
SMART
  
PROSITE
  
PRINTS