Tag | Content |
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CPLM ID | CPLM-004896 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome b-c1 complex subunit Rieske, mitochondrial |
Protein Synonyms/Alias | Complex III subunit 5; Cytochrome b-c1 complex subunit 5; Liver regeneration-related protein LRRGT00195; Rieske iron-sulfur protein; RISP; Ubiquinol-cytochrome c reductase iron-sulfur subunit; Cytochrome b-c1 complex subunit 11; Complex III subunit IX; Ubiquinol-cytochrome c reductase 8 kDa protein |
Gene Name | Uqcrfs1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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46 | EPPVLDVKRPFLCRE | acetylation | [1] | 101 | AEVLDSTKSSKESSE | acetylation | [1] | 155 | AMSKIEIKLSDIPEG | acetylation | [1] | 163 | LSDIPEGKNMAFKWR | acetylation | [1] | 168 | EGKNMAFKWRGKPLF | acetylation | [1] | 172 | MAFKWRGKPLFVRHR | acetylation | [1] | 182 | FVRHRTKKEIDQEAA | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. |
Sequence Annotation | DOMAIN 187 272 Rieske. METAL 217 217 Iron-sulfur (2Fe-2S) (By similarity). METAL 219 219 Iron-sulfur (2Fe-2S); via pros nitrogen METAL 236 236 Iron-sulfur (2Fe-2S) (By similarity). METAL 239 239 Iron-sulfur (2Fe-2S); via pros nitrogen DISULFID 222 238 By similarity. |
Keyword | 2Fe-2S; Complete proteome; Direct protein sequencing; Disulfide bond; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Reference proteome; Respiratory chain; Transit peptide; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 274 AA |
Protein Sequence | MLSVAARSGP FAPVLSATSR GVAGALRPLL QSAVPATSEP PVLDVKRPFL CRESLSGQAA 60 TRPLVATVGL NVPASVRYSH TDIKVPDFSD YRRAEVLDST KSSKESSEAR KGFSYLVTAT 120 TTVGVAYAAK NAVSQFVSSM SASADVLAMS KIEIKLSDIP EGKNMAFKWR GKPLFVRHRT 180 KKEIDQEAAV EVSQLRDPQH DLERVKKPEW VILIGVCTHL GCVPIANAGD FGGYYCPCHG 240 SHYDASGRIR KGPAPLNLEV PTYEFTSGDV VVVG 274 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005750; C:mitochondrial respiratory chain complex III; IDA:RGD. GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0032403; F:protein complex binding; IDA:RGD. GO:0008121; F:ubiquinol-cytochrome-c reductase activity; TAS:RGD. GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. GO:0046677; P:response to antibiotic; IEP:RGD. GO:0042493; P:response to drug; IEP:RGD. GO:0009725; P:response to hormone stimulus; IEP:RGD. |
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