CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038358
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myh15 
Protein Synonyms/Alias
  
Gene Name
 Myh15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
933ELTARGRKLEDECSEubiquitination[1]
1401AMEVSNAKNASLERAubiquitination[1]
1775AHLERMRKNMEQTIKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1925 AA 
Protein Sequence
MDLSEFGDAT AFLRRNKADP LFQPPAFDGK KKCWVPDGKN AYIEAEVKES GDDGQVIVET 60
RDGEIMRIKE DKLQQMNPEE LEMIEDLSML LYLNEASVLH TLRRRYDHWM IYTYSGIFCV 120
AINPYKWLPV YQKEVMAAYK RKRRSEVPPH IFAVANRAFQ DMLRNGENQS IVFTGESGSG 180
KTVNTKLIIQ YFATMAAISE PKKKLGNLED QIVKMNPLLE AFGNAKTQKN DNSSRFGKLI 240
RIHFGARGTL SFADIQIYFL EKSRVVYQQP GERNYHIFYQ ILSGNQELRN MLLVSTNPSD 300
FHICSCGVVA VESLDDAKEF LATEKAIDVL GFLPDEKFGC YKLVGAIMHF GNLKFKRNLR 360
EEQLEADGTE NADKAAFLMG IHASELLKGL IYPRIKVGNE YVTRSQNLQQ VTYAVGALSQ 420
SIYERMFQWL VARMNQVLDA KLTSHFFVGI LDTTGFEILD YNSLEQLCIN FTNEKLQQFF 480
NQQLFILEQE EYRKEGLDWL SIDYGLDVQA CIDFIEKPMG IFSILEEECM LPKATDQMFK 540
TKLFDHHFGK SAYFQTPTSP EKNFEVHFEL AHYAGVVPYN ISGWIGKNKG LLNETVVALL 600
QKSSNKVLAN LFTKDIIAGS ASQFGEKTHK KGTSFHLITS LHKENINKLM TDLKSTAPHF 660
VRCINPNKNK IPGVMDPFLV LQQLRCNGVL EGIRVCCEAF PSWMLYDDFK QRYWILNPRI 720
FSKSKFVSSR KATEEVLDFL EIDHPHYQCG VTKVFFKAFI LDQLEERRDE KISKVFTLFQ 780
ARARGKLMRI TFQKILEERD ALALIQENIR AFIAVKNCPW MGLFFKIKPL AKSVGAGEEI 840
AGLKEECAQL QKALESSESQ REELKTKQVS LVQEKNDLRL QLQAEQETLA NSEEQCESLI 900
KSKVELEVKI KELSRQVEEE EEINSELTAR GRKLEDECSE LKKEIYDLEA ILAKSEKGKC 960
AAEHKVRNLT EEVHSLNEEV SKLSRVVKDA QETQQQTQEQ LHIEEEKLSN MSKANLKLAQ 1020
QIDVLEGDLE RERKARMKCE REKRKLQDEL KMNQEGAENL ESSRQKLAEQ LRKKEFEMGQ 1080
MNSKVENEKN QVSQLQKMVK ELQTHILNLK EELESERTIR AKVEREKGDL VQDLEDLNER 1140
LEEAGGTSLA QMEITKQQEA RFQKLHHDME ETTRHFEATS ASLKKRHAEN LAELEGQVEH 1200
LQQVRLVLEQ DKSDLQLQVD DLLNRVDQMA RAKANAEKLC GLYERRLNEA NTKLDEVTQL 1260
AHDLTTQKTK LQSESGEFFK RLEEKEALIS QLSREKSNFT RQVEELRAQL EEESRSQSAL 1320
SHALQSAKHD YDLLREQYEE EQEVKAELHR ALSKGNKETV QWRAKYEHDA MQRTEDLEEA 1380
KKKLAIRLQE AAEAMEVSNA KNASLERARH RLQLELGDAL SDLGKARSVA AALGQKQQHS 1440
DKALTSWKQK LDETQELLQA SQKETRALSS EVLTFRQACE ESTEAQETLK RQNQDLQEQI 1500
CSLTNQVREG IKNLAEVEKA KKLIEQEKTE VQVRLEETEG ALERNESKIL RFQLELSEAK 1560
AELERKLSEK EEEAERLREK HQQAMGSLQS NLDLEASSRI EATRLRKKME GDLKEMEIQL 1620
CAANRQVSQM TRALGQLQGQ MKDLHQQLDD SIYQNKDLKE QVALAEQRTV LLQSELEELR 1680
TLQEQTERGR KLAEKELLEA TERINLFHTQ NTSLLSQKKK LEADVAQVQK EAGEMLQACQ 1740
KAEEKAKKTA AEAANMSEEL KKEQDTNAHL ERMRKNMEQT IKDLQKRLDE AEQTAVLGSK 1800
KQIQKLESRV RDLEGELESE VRRSAEAQRE ARRLERGIKE LTYQAEEDKK NLSRMQALSD 1860
KLQLKVQSYK QQVEAAEAQA NQYLSKYKKQ QHELNEAKER AEAAESQVNK LRAKAKELEK 1920
KVREE 1925 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR015650; Myosin_1/23/4/7/8/13/15.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.