CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040006
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin thioesterase OTUB1 
Protein Synonyms/Alias
  
Gene Name
 OTUB1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
80DDNIYQQKIKDLHKKubiquitination[1]
118EALLDDSKELQRFKAubiquitination[1]
197GYLQRESKFFEHFIEubiquitination[1]
210IEGGRTVKEFCQQEVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 280 AA 
Protein Sequence
MAAEEPQQQK QEPLGSDSEG VNCLAYDEAI MAQQDRIQQE DMTDPCLLQI AVQNPLVSER 60
LELSVLYKEY AEDDNIYQQK IKDLHKKYSY IRKTRPDGNC FYRAFGFSHL EALLDDSKEL 120
QRFKAVSAKS KEDLVSQGFT EFTIEDFHNT FMDLIEQVEK QTSVADLLAS FNDQSTSDYL 180
VVYLRLLTSG YLQRESKFFE HFIEGGRTVK EFCQQEVEPM CKESDHIHII ALAQALSVSI 240
QVEYMDRGEG GTTNPHIFPE GSEPKVYLLY RPGHYDILYK 280 
Gene Ontology
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0019538; P:protein metabolic process; IEA:InterPro. 
Interpro
 IPR003323; OTU.
 IPR019400; Peptidase_C65_otubain.
 IPR016615; Ubiquitin_thioesterase_Otubain. 
Pfam
 PF10275; Peptidase_C65 
SMART
  
PROSITE
 PS50802; OTU 
PRINTS