| Tag | Content |
|---|
| CPLM ID | CPLM-022826 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Xenotropic and polytropic retrovirus receptor 1 |
Protein Synonyms/Alias | Protein SYG1 homolog; Xenotropic and polytropic murine leukemia virus receptor X3; X-receptor |
Gene Name | XPR1 |
Gene Synonyms/Alias | SYG1; XR |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 48 | VTDEDTVKRYFAKFE | ubiquitination | [1] | | 76 | INTFYSEKLAEAQRR | ubiquitination | [1] | | 99 | QSSLDAQKESTGVTT | ubiquitination | [1] | | 474 | MDWGLFDKNAGENTF | ubiquitination | [1] | | 619 | QSKARDTKVLIEDTD | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses. |
Sequence Annotation | DOMAIN 1 177 SPX.
DOMAIN 439 643 EXS.
MOD_RES 668 668 Phosphoserine.
MOD_RES 690 690 Phosphothreonine. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Host cell receptor for virus entry; Membrane; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 696 AA |
Protein Sequence | MKFAEHLSAH ITPEWRKQYI QYEAFKDMLY SAQDQAPSVE VTDEDTVKRY FAKFEEKFFQ 60
TCEKELAKIN TFYSEKLAEA QRRFATLQNE LQSSLDAQKE STGVTTLRQR RKPVFHLSHE 120
ERVQHRNIKD LKLAFSEFYL SLILLQNYQN LNFTGFRKIL KKHDKILETS RGADWRVAHV 180
EVAPFYTCKK INQLISETEA VVTNELEDGD RQKAMKRLRV PPLGAAQPAP AWTTFRVGLF 240
CGIFIVLNIT LVLAAVFKLE TDRSIWPLIR IYRGGFLLIE FLFLLGINTY GWRQAGVNHV 300
LIFELNPRSN LSHQHLFEIA GFLGILWCLS LLACFFAPIS VIPTYVYPLA LYGFMVFFLI 360
NPTKTFYYKS RFWLLKLLFR VFTAPFHKVG FADFWLADQL NSLSVILMDL EYMICFYSLE 420
LKWDESKGLL PNNSEERGHS DTMVFFYLWI VFYIISSCYT LIWDLKMDWG LFDKNAGENT 480
FLREEIVYPQ KAYYYCAIIE DVILRFAWTI QISITSTTLL PHSGDIIATV FAPLEVFRRF 540
VWNFFRLENE HLNNCGEFRA VRDISVAPLN ADDQTLLEQM MDQDDGVRNR QKNRSWKYNQ 600
SISLRRPRLA SQSKARDTKV LIEDTDDEAN T 631 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc. GO:0009615; P:response to virus; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |