| Tag | Content |
|---|
| CPLM ID | CPLM-006104 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit |
Protein Synonyms/Alias | GlcNAc-PI synthesis protein |
Gene Name | SPT14 |
Gene Synonyms/Alias | CWH6; GPI3; YPL175W; P2269 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 159 | ICVSNTCKENMIVRT | ubiquitination | [1] | | 186 | AVVSEDFKPRDPTGG | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Glycosyltransferase; GPI-anchor biosynthesis; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 452 AA |
Protein Sequence | MGFNIAMLCD FFYPQLGGVE FHIYHLSQKL IDLGHSVVII THAYKDRVGV RHLTNGLKVY 60
HVPFFVIFRE TTFPTVFSTF PIIRNILLRE QIQIVHSHGS ASTFAHEGIL HANTMGLRTV 120
FTDHSLYGFN NLTSIWVNKL LTFTLTNIDR VICVSNTCKE NMIVRTELSP DIISVIPNAV 180
VSEDFKPRDP TGGTKRKQSR DKIVIVVIGR LFPNKGSDLL TRIIPKVCSS HEDVEFIVAG 240
DGPKFIDFQQ MIESHRLQKR VQLLGSVPHE KVRDVLCQGD IYLHASLTEA FGTILVEAAS 300
CNLLIVTTQV GGIPEVLPNE MTVYAEQTSV SDLVQATNKA INIIRSKALD TSSFHDSVSK 360
MYDWMDVAKR TVEIYTNISS TSSADDKDWM KMVANLYKRD GIWAKHLYLL CGIVEYMLFF 420
LLEWLYPRDE IDLAPKWPKK TVSNETKEAR ET 452 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0000506; C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; TAS:SGD. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:EC. GO:0008194; F:UDP-glycosyltransferase activity; IPI:SGD. GO:0006506; P:GPI anchor biosynthetic process; ISS:SGD. |
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