| Tag | Content |
|---|
| CPLM ID | CPLM-006090 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Signaling mucin MSB2 |
Protein Synonyms/Alias | Multicopy suppressor of bud emergence 2; Osmosensor MSB2 |
Gene Name | MSB2 |
Gene Synonyms/Alias | YGR014W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1223 | IQSQEIIKNPEISSI | ubiquitination | [1] | | 1239 | SSEFGGEKNYNNEKR | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Plasma membrane signaling mucin that promotes activation of the MAPK for the filamentous growth pathway. Partially redundant with the SHO1 osmosensing branch for the activation of STE11. |
Sequence Annotation | REPEAT 698 714 1.
REPEAT 715 731 2.
REPEAT 732 748 3.
REPEAT 749 765 4.
REPEAT 766 782 5.
REPEAT 783 799 6.
REPEAT 800 816 7.
REGION 698 816 7 X 17 AA tandem repeats.
MOD_RES 1300 1300 Phosphoserine.
CARBOHYD 30 30 N-linked (GlcNAc...) (Potential).
CARBOHYD 859 859 N-linked (GlcNAc...) (Potential).
CARBOHYD 885 885 N-linked (GlcNAc...) (Potential).
CARBOHYD 945 945 N-linked (GlcNAc...) (Potential).
CARBOHYD 1049 1049 N-linked (GlcNAc...) (Potential).
CARBOHYD 1088 1088 N-linked (GlcNAc...) (Potential).
CARBOHYD 1175 1175 N-linked (GlcNAc...) (Potential). |
Keyword | Cell membrane; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1306 AA |
Protein Sequence | MQFPFACLLS TLVISGSLAR ASPFDFIFGN GTQQAQSQSE SQGQVSFTNE ASQDSSTTSL 60
VTAYSQGVHS HQSATIVSAT ISSLPSTWYD ASSTSQTSVS YASQESDYAV NQNSWSASTN 120
QLPSTSTTSY YAPTFSTSAD FAASSVNAAS DVSTASVPID TSANSIPFTT TSNIETTTSA 180
PLTSDTPLIS TSTMSAADNV FSSANPISAS LTTTDSSESF DQTSTAGAIP VQSSADFSSS 240
SEILVQSSAD FSSPSSPTTT DISLSAAPLQ TSESSSFTTA SAALPVSSTD VDGSSASPVV 300
SMSAAGQIAS SSSTDNPTMS ETFSLTSTEV DGSDVSSTVS ALLSAPFLQT STSNSFSIVS 360
PSVSFVPSQS SSDVASSSTA NVVSSSFSDI PPQTSTSGSV VSVAQSASAL AFQSSTEVYG 420
ASASSTMSSL LSTTSLQSTT LDSSSLASSS ASSSDLTDYG VSSTASIPLL SASEQASTSS 480
SFSVVSPSVS FVPSQSSSDV ASTSAPSVVS SSFSYTSLQA GGSSMTNPSS STIVYSSSTG 540
SSEESAASTA SATLSGSSST YMAGNLQSQP PSTSSLLSES QATSTSAVLA SSSVSTTSPY 600
TTAGGASTEA SSLISSTSAE TSQVSYSQST TALQTSSFAS SSTTEGSETS SQGFSTSSVL 660
VQMPSSISSE FSPSQTTTQM NSASSSSQYT ISSTGILSQV SDTSVSYTTS SSSVSQVSDT 720
PVSYTTSSSS VSQVSDTPVS YTTSSSSVSQ VSDTPVSYTT SSSSVSQVSD TPVSYTTSSS 780
SVSQVSDTSV PSTSSRSSVS QVSDTPVPST SSRSSVSQTS SSLQPTTTSS QRFTISTHGA 840
LSESSSVSQQ ASEITSSINA TASEYHSIQT TAATQSTTLS FTDANSSSAS APLEVATSTP 900
TPSSKASSLL LTPSTSSLSQ VATNTNVQTS LTTESTTVLE PSTTNSSSTF SLVTSSDNNW 960
WIPTELITQA PEAASTASST VGGTQTMTLP HAIAAATQVP EPEGYTLITI GFKKALNYEF 1020
VVSEPKSSAQ IFGYLPEALN TPFKNVFTNI TVLQIVPLQD DSLNYLVSVA EVYFPTAEIE 1080
ELSNLITNSS SAFYTDGMGT AKSMAAMVDS SIPLTGLLHD SNSNSGGSSD GSSSSNSNSG 1140
SSGSGSNSNS GVSSSSGNSY QDAGTLEYSS KSNSNVSTSS KSKKKIIGLV IGVVVGGCLY 1200
ILFMIFAFKY IIRRRIQSQE IIKNPEISSI SSSEFGGEKN YNNEKRMSVQ ESITQSMRIQ 1260
NWMDDSYYGH GLTNNDSTPT RHNTSSSIPK ISRPIASQNS LGWNEV 1306 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IMP:SGD. GO:0030427; C:site of polarized growth; IDA:SGD. GO:0005034; F:osmosensor activity; IMP:SGD. GO:0030010; P:establishment of cell polarity; IMP:SGD. GO:0006972; P:hyperosmotic response; IGI:SGD. GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IGI:SGD. GO:0001402; P:signal transduction involved in filamentous growth; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |