UniProt Accession

 OGFR_MOUSE; Q99PG2; A2ACT6; Q99L33 

Genbank Protein ID

 AF303894; AL669926; BC003875 

Genbank Nucleotide ID

 AAK01353.1; CAM26816.1; AAH03875.1 

Protein Name

 Opioid growth factor receptor 

Protein Synonyms/Alias

 OGFr; Zeta-type opioid receptor 

Gene Name

 Ogfr 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
142	HAKPLTLKEVEAFKS	acetylation	[1, 2]
142	HAKPLTLKEVEAFKS	ubiquitination	[3]
235	EETLVQHKLPSVRQS	ubiquitination	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation (By similarity). 

Sequence Annotation

 REPEAT 467 475 1.
 REPEAT 476 484 2.
 REPEAT 485 493 3.
 REPEAT 494 502 4.
 REPEAT 503 511 5.
 REPEAT 512 520 6.
 REPEAT 521 529 7.
 REPEAT 530 538 8.
 REPEAT 539 547 9.
 REPEAT 548 556 10.
 REPEAT 557 565 11.
 REPEAT 566 574 12.
 REPEAT 575 583 13.
 REPEAT 584 592 14.
 REGION 467 592 14 X approximate tandem repeats.
 MOTIF 257 286 Bipartite nuclear localization signal
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 361 361 Phosphoserine (By similarity).
 MOD_RES 403 403 Phosphoserine (By similarity).
 MOD_RES 452 452 Phosphoserine (By similarity).  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Growth regulation; Nucleus; Phosphoprotein; Receptor; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 633 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. 

Interpro

 IPR006757; OGF_rcpt. 

Pfam

 PF04664; OGFr_N 

SMART

  

PROSITE

  

PRINTS