CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021664
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribonucleoprotein PTB-binding 2 
Protein Synonyms/Alias
 Protein raver-2 
Gene Name
 RAVER2 
Gene Synonyms/Alias
 KIAA1579 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
581PKEIRLSKNPYLNLAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May bind single stranded nucleic acids (Potential). 
Sequence Annotation
 DOMAIN 69 140 RRM 1.
 DOMAIN 142 220 RRM 2.
 DOMAIN 231 309 RRM 3.
 MOD_RES 2 2 N-acetylalanine.  
Keyword
 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 691 AA 
Protein Sequence
MAAAAGDGGG EGGAGLGSAA GLGPGPGLRG QGPSAEAHEG APDPMPAALH PEEVAARLQR 60
MQRELSNRRK ILVKNLPQDS NCQEVHDLLK DYDLKYCYVD RNKRTAFVTL LNGEQAQNAI 120
QMFHQYSFRG KDLIVQLQPT DALLCITNVP ISFTSEEFEE LVRAYGNIER CFLVYSEVTG 180
HSKGYGFVEY MKKDFAAKAR LELLGRQLGA SALFAQWMDV NLLASELIHS KCLCIDKLPS 240
DYRDSEELLQ IFSSVHKPVF CQLAQDEGSY VGGFAVVEYS TAEQAEEVQQ AADGMTIKGS 300
KVQVSFCAPG APGRSTLAAL IAAQRVMHSN QKGLLPEPNP VQIMKSLNNP AMLQVLLQPQ 360
LCGRAVKPAV LGTPHSLPHL MNPSISPAFL HLNKAHQSSV MGNTSNLFLQ NLSHIPLAQQ 420
QLMKFENIHT NNKPGLLGEP PAVVLQTALG IGSVLPLKKE LGHHHGEAHK TSSLIPTQTT 480
ITAGMGMLPF FPNQHIAGQA GPGHSNTQEK QPATVGMAEG NFSGSQPYLQ SFPNLAAGSL 540
LVGHHKQQQS QPKGTEISSG AASKNQTSLL GEPPKEIRLS KNPYLNLASV LPSVCLSSPA 600
SKTTLHKTGI ASSILDAISQ GSESQHALEK CIAYSPPFGD YAQVSSLRNE KRGSSYLISA 660
PEGGSVECVD QHSQGTGAYY METYLKKKRV Y 691 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS