UniProt Accession

 BTUE_ECOLI; P06610 

Genbank Protein ID

 M14031; U00096; AP009048 

Genbank Nucleotide ID

 AAA23527.1; AAC74780.1; BAA15478.1 

Protein Name

 Vitamin B12 transport periplasmic protein BtuE 

Protein Synonyms/Alias

  

Gene Name

 btuE 

Gene Synonyms/Alias

 b1710; JW1700 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
51	EQLENIQKAWVDRGF	acetylation	[1]
96	VTFPMFSKIEVNGEG	acetylation	[1]
110	GRHPLYQKLIAAAPT	acetylation	[1]
178	PIVMESIKLALAK**	acetylation	[1, 2]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

 Not essential for B12 transport; however, it is an auxiliary component of the transport system. 

Sequence Annotation

  

Keyword

 Cobalt; Cobalt transport; Complete proteome; Ion transport; Oxidoreductase; Periplasm; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 183 AA 

Protein Sequence

Gene Ontology

 GO:0042597; C:periplasmic space; IDA:EcoliWiki.
 GO:0004602; F:glutathione peroxidase activity; IDA:EcoCyc.
 GO:0008379; F:thioredoxin peroxidase activity; IDA:EcoCyc.
 GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
 GO:0033194; P:response to hydroperoxide; IEP:EcoCyc. 

Interpro

 IPR000889; Glutathione_peroxidase.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00255; GSHPx 

SMART

  

PROSITE

 PS00460; GLUTATHIONE_PEROXID_1
 PS00763; GLUTATHIONE_PEROXID_2
 PS51355; GLUTATHIONE_PEROXID_3 

PRINTS

 PR01011; GLUTPROXDASE.