CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037296
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Integrin-linked kinase-associated serine/threonine phosphatase 2C 
Protein Synonyms/Alias
  
Gene Name
 ILKAP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
159HGGIRASKFAAQNLHubiquitination[1]
208LKQASSQKPAWK***acetylation[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 212 AA 
Protein Sequence
MDLFGDLPEP ERSPRPAAGK EAQKGPLLFD DLPPASSTDS GSGGPLLFDD LPPASSGDSG 60
SLATSISQMV KTEGKGAKRK TSEEEKNGSE ELVEKKVSSS VIFGLKGYVA ERKGEREEMQ 120
DAHVILNDIT EECRPPSSLI TRVSYFAVFD GHGGIRASKF AAQNLHQNLI RKFPKGDVIS 180
VEKTVKRCLL DTFKHTDEEF LKQASSQKPA WK 212 
Gene Ontology
 GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
 GO:0006470; P:protein dephosphorylation; IEA:InterPro. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C 
SMART
  
PROSITE
 PS01032; PP2C 
PRINTS