CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040952
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Eukaryotic translation initiation factor 6 
Protein Synonyms/Alias
  
Gene Name
 EIF6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54GEACAGVKSSGSGRVubiquitination[1, 2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 186 AA 
Protein Sequence
MAVRASFENN CEIGCFAKLT NTYCLVAIGG SENFYRCGGS PGAYGGGEAC AGVKSSGSGR 60
VPAPLPRHHR VHVPTVCSRA SSPIPSPWCT RLSPAAASSG ACVWGTGTVS WYPTIPPTRS 120
CNTFATASQT QCRLGGWRSG SQPWAMSPPA MTTWPWSTQT WTGRQKKFWQ MCSRWKSSDR 180
QWPTRC 186 
Gene Ontology
 GO:0043022; F:ribosome binding; IEA:InterPro.
 GO:0042256; P:mature ribosome assembly; IEA:InterPro. 
Interpro
 IPR002769; eIF6. 
Pfam
  
SMART
  
PROSITE
  
PRINTS