CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015056
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 
Protein Synonyms/Alias
 ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta 
Gene Name
 accD 
Gene Synonyms/Alias
 RPA0071 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
27TPENLWIKCPDTGQLacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 
Functional Description
 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity). 
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Cytoplasm; Fatty acid biosynthesis; Fatty acid metabolism; Ligase; Lipid biosynthesis; Lipid metabolism; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 327 AA 
Protein Sequence
MNWLTNVVRP KIRNILRRET PENLWIKCPD TGQLVFYKDV EQNQFVIPGS NYHMRMGAVA 60
RLRAIFDNET WYDVALPEVV ADPLKFRDER KYADRIKDAR TKTGAHDAVR VGFGKLETSP 120
VVVAVQDFDF MGGSLGMAAG EAIIRGMELA VEKHAPFIMF AASGGARMQE GILSLMQMPR 180
TTVAVQMLRE AKLPYIVVLT NPTTGGVTAS YAMLGDIHIA EPGALIGFAG ARVIEQTIRE 240
KLPDGFQRAE YLKEHGMVDM VVHRHDLRPT LARLCRLLTK SPALTVTTAV EAPAEAAAKA 300
EPEATTTEQP GAPAPTEPPA QPAAPQA 327 
Gene Ontology
 GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
 GO:0003989; F:acetyl-CoA carboxylase activity; IEA:HAMAP.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006633; P:fatty acid biosynthetic process; IEA:HAMAP.
 GO:2001295; P:malonyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR000438; Acetyl_CoA_COase_Trfase_b_su.
 IPR000022; Carboxyl_trans.
 IPR011762; COA_CT_N. 
Pfam
 PF01039; Carboxyl_trans 
SMART
  
PROSITE
 PS50980; COA_CT_NTER 
PRINTS
 PR01070; ACCCTRFRASEB.