CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025714
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transferrin receptor, isoform CRA_a 
Protein Synonyms/Alias
  
Gene Name
 Tfrc 
Gene Synonyms/Alias
 mCG_129940 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
39DNSHVEMKLAADEEEubiquitination[1]
53ENADNNMKASVRKPKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Receptor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 763 AA 
Protein Sequence
MMDQARSAFS NLFGGEPLSY TRFSLARQVD GDNSHVEMKL AADEEENADN NMKASVRKPK 60
RFNGRLCFAA IALVIFFLIG FMSGYLGYCK RVEQKEECVK LAETEETDKS ETMETEDVPT 120
SSRLYWADLK TLLSEKLNSI EFADTIKQLS QNTYTPREAG SQKDESLAYY IENQFHEFKF 180
SKVWRDEHYV KIQVKSSIGQ NMVTIVQSNG NLDPVESPEG YVAFSKPTEV SGKLVHANFG 240
TKKDFEELSY SVNGSLVIVR AGEITFAEKV ANAQSFNAIG VLIYMDKNKF PVVEADLALF 300
GHAHLGTGDP YTPGFPSFNH TQFPPSQSSG LPNIPVQTIS RAAAEKLFGK MEGSCPARWN 360
IDSSCKLELS QNQNVKLIVK NVLKERRILN IFGVIKGYEE PDRYVVVGAQ RDALGAGVAA 420
KSSVGTGLLL KLAQVFSDMI SKDGFRPSRS IIFASWTAGD FGAVGATEWL EGYLSSLHLK 480
AFTYINLDKV VLGTSNFKVS ASPLLYTLMG KIMQDVKHPV DGKSLYRDSN WISKVEKLSF 540
DNAAYPFLAY SGIPAVSFCF CEDADYPYLG TRLDTYEALT QKVPQLNQMV RTAAEVAGQL 600
IIKLTHDVEL NLDYEMYNSK LLSFMKDLNQ FKTDIRDMGL SLQWLYSARG DYFRATSRLT 660
TDFHNAEKTN RFVMREINDR IMKVEYHFLS PYVSPRESPF RHIFWGSGSH TLSALVENLK 720
LRQKNITAFN ETLFRNQLAL ATWTIQGVAN ALSGDIWNID NEF 763 
Gene Ontology
 GO:0005905; C:coated pit; IEA:Compara.
 GO:0016023; C:cytoplasmic membrane-bounded vesicle; ISO:MGI.
 GO:0005768; C:endosome; IDA:MGI.
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0070062; C:extracellular vesicular exosome; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0005381; F:iron ion transmembrane transporter activity; TAS:MGI.
 GO:0008233; F:peptidase activity; IEA:InterPro.
 GO:0004998; F:transferrin receptor activity; TAS:MGI.
 GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR007484; Peptidase_M28.
 IPR003137; Protease-assoc_domain.
 IPR007365; TFR-like_dimer_dom. 
Pfam
 PF02225; PA
 PF04389; Peptidase_M28
 PF04253; TFR_dimer 
SMART
  
PROSITE
  
PRINTS