CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027053
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cheerio, isoform G 
Protein Synonyms/Alias
  
Gene Name
 cher 
Gene Synonyms/Alias
 CG3937; Dmel_CG3937 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
543AKSPFEVKVGPKKESacetylation[1]
1136AYGPGLEKGLTNQKNacetylation[1]
1395CSIKYGDKEIEGSPFacetylation[1]
1403EIEGSPFKLEAFPTGacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2399 AA 
Protein Sequence
MEAERDLAED AQWKKIQQNT FTRWANEHLK TIDRSINNLE TDLSDGLRLI ALIEVLSQKR 60
MPKYNKRPTF RSQKLENVSV ALKFLQDEGI KIVNIDSSDI VDCKLKLILG LIWTLILHYS 120
ISMPMWDGED DKQLNGSGHT PKQRLLNWIH AKIPDLPINN FTNDWTTGKA VGALVDACAP 180
GLCPDWELWD PKDAVQNASE AMGLADDWLN VRQLIKPEEL VNPNVDEQSM MTYLSQYPNS 240
KLKTGAPLRP KTNPNRVRAY GPGIEPIGPV VGAPANFTVE TFSAGKGSVD VDIQGPNGEI 300
EKADVRFNND KNLTYTVSYI PKSEGSHKVA VKFSGRDIPK SPFPVKVEGH AGDASKVKVT 360
GPGIQPNGVT IKKPTFFDIL AKDAGRGVPE VIIIDPANHK TSVAAKVRQL ENDTWRCEYV 420
TALQGLHSVN VFYAGTPIPN SPFPVKVAPL SDARKVRASG RGLQATGVRV GDDADFKIYT 480
EGAGEGEPEV RVIGPGGMNQ NVMQSKVDGN TYECHYYPTK EGRYVIMVTF AGQEVAKSPF 540
EVKVGPKKES SIVAYGPGLS SGVIGYPAAF VVETNGETGA LGFTVAGPSQ AEIECHDNGD 600
GSALVKYHPT AVGEYAVHIL CDNEDIPKSP FIAQILPRTD FHPELVKASG PGLEKNGVTI 660
NQPTSFTVDP SKAGNAPLDV VVQDVFGTKL PVELKNNPDG TKKVTYTPTS GVPHTVEVNY 720
GGVSTPNSPH RVYVGVPVDA AKVQAFGPWL QPGVRPNAAT HFNVDAREAG DAELKVKIIH 780
EETKIEVPCR IIDNEDNTYS VEVIPPSKGA YTTTMTYGGQ RVPLGEKVVV EQTVDVSKIK 840
VDGLEPTAPL NSLQQFRIIT HGLPKADLAV TITSPSGNRI KAHIIPTAEG FLVNFTPTQL 900
GEYLLSICFG GTPITPRPFR LQCLTGSDSN KVQAFGPGLE RGIVGQPAEF MIDTRGAGQG 960
GLGVTVEGPC EAAINCRDNG DGTCNVAYLP TEAGDYTVNI TFNERHITGS PFQPLIVPVP 1020
NLKNTRVSGI GIQPHGVIMN AATDFMVDMS KVGSNIDSGK LSCAIFDPMG HVLPSKIVQG 1080
PTDDIFRIMY TPFEAGRHTI ELMYDNIPVP GSPFVVNVKS GCDPARCKAY GPGLEKGLTN 1140
QKNKFTVETK GAGNGGLSLA IEGPSEAKMT CTDNRDGSCD VDYLATDPGE YDITIRFADK 1200
HIPGSPFRVL VEETVDPSKV KVYGPGIEHG QVRESVPTFF NVDVGEAGPG RIAVKLTNSE 1260
GIPVDNLRVE DKGNCIYAVH YVPPKAGSVL TCQVKFSEVE VPCSPFVMTV FPKSEPTKVK 1320
VKGVNEKKKT PASLPAEFEI DTKQAGQADI NVAIKNPKGK AMQPRLEEVS TGTYVVSFVP 1380
DECGTYQCSI KYGDKEIEGS PFKLEAFPTG EAKKCKLVEQ APKIQTSGSQ SHLKVDAREA 1440
GDGAVTCKIT NKAGSEIVDI DVIEKDGFFD ILYALNDPGD YDINVKFGGK DIPNGSFSIK 1500
AVESIEQYSH SEYIEEHTTK VVQQTTQSEL VNGKSEITYR SVAFEKLPLP TTGGNVTAEV 1560
RMPSGKVDKP VIQDNRDGTV SVKYDPREEG SHELVVKYNG EPVQGSPFKF HVDSITSGYV 1620
TAYGPGLTHG VTGEPANFTI STKGASAGGL TMAVEGPSKA DINYHDNKDG TVSVQYLPTA 1680
PGEYQVSVRF GDKHIKGSPY FAKITGEGRK RNQISVGSCS EVTMPGDITD DDLRALNASI 1740
QAPSGLEEPC FLKRMPTGNI GISFTPREIG EHLVSVKRLG KHINNSPFKV TVCEREVGDA 1800
KKVKVSGTGL KEGQTHADNI FSVDTRNAGF GGLSVSIEGP SKAEIQCTDK DDGTLNISYK 1860
PTEPGYYIVN LKFADHHVEG SPFTVKVAGE GSNRKREKIQ RERDAVPITE IGSQCKLTFK 1920
MPGITSFDLA ACVTSPSNVT EDAEIQEVED GLYAVHFVPK ELGVHTVSVR YSEMHIPGSP 1980
FQFTVGPLRD SGSHLVKAGG SGLERGVVGE AAEFNVWTRE AGGGSLAISV EGPSKADIEF 2040
KDRKDGSCDV SYKVTEPGEY RVGLKFNDRH IPDSPFKVYV SPDAGDAHKL EVQQFPQGNI 2100
QADAPYQFMV RKNGAKGELD AKIVAPSGTD DDCFIQVIDG EMYSVRFYPR ENGIHAIHVK 2160
FNGVHIPDSP FRIKVGKDVA DPAAVHASGN GLDEVKTGHK ADFIINTCNA GVGTLAVSID 2220
GPSKVAMDCT EVEEGYKVRY TPLLPGEHYI TVKYNNMHIV GSPFKVNATG DKLADEGAQE 2280
TSTVIVETVQ KVAKGGKNTG VHLPTFKSDA SKVVSKGMGL KKAYIGKQNQ FSISATDAGN 2340
NILYVGMYGP KGPCEEFHVK HAGHNNYNVQ YLVRDRGQYV LLIKWGEEHI PGSPFQIDV 2399 
Gene Ontology
 GO:0035183; C:female germline ring canal inner rim; IDA:FlyBase.
 GO:0035182; C:female germline ring canal outer rim; IDA:FlyBase.
 GO:0003779; F:actin binding; ISS:FlyBase.
 GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.
 GO:0008340; P:determination of adult lifespan; IMP:FlyBase.
 GO:0008302; P:female germline ring canal formation, actin assembly; IMP:FlyBase.
 GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.
 GO:0007067; P:mitosis; IMP:FlyBase.
 GO:0008045; P:motor neuron axon guidance; IMP:FlyBase.
 GO:0035204; P:negative regulation of lamellocyte differentiation; IMP:FlyBase.
 GO:0008355; P:olfactory learning; IMP:FlyBase.
 GO:0008104; P:protein localization; IMP:FlyBase. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set. 
Pfam
 PF00307; CH
 PF00630; Filamin 
SMART
 SM00033; CH
 SM00557; IG_FLMN 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS50194; FILAMIN_REPEAT 
PRINTS