UniProt Accession

 Q7KQK6_PLAF7; Q7KQK6 

Genbank Protein ID

 AE014186 

Genbank Nucleotide ID

 AAN35767.1 

Protein Name

 GTP-binding nuclear protein ran/tc4 

Protein Synonyms/Alias

  

Gene Name

 Ran 

Gene Synonyms/Alias

 PF11_0183 

Created Date

 July 27, 2013 

Organism

 Plasmodium falciparum (isolate 3D7) 

NCBI Taxa ID

 36329 

Lysine Modification

Position	Peptide	Type	References
37	LTGEFEKKYIPTLGV	acetylation	[1]
70	WDTAGQEKFGGLRDG	acetylation	[1]
181	VFVGEHAKAPEFQID	acetylation	[1]
197	NIVREAEKELEQAAA	acetylation	[1]

Reference

 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 214 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; ISS:GeneDB_Pfalciparum.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; ISS:GeneDB_Pfalciparum.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0051726; P:regulation of cell cycle; ISS:GeneDB_Pfalciparum.
 GO:0006405; P:RNA export from nucleus; ISS:GeneDB_Pfalciparum.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR002041; Ran_GTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase. 

Pfam

 PF00071; Ras 

SMART

 SM00176; RAN 

PROSITE

 PS51418; RAN 

PRINTS

 PR00627; GTPRANTC4.