CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039285
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Tgm6 
Protein Synonyms/Alias
  
Gene Name
 Tgm6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
553LRESHTMKLGPLEEKubiquitination[1]
560KLGPLEEKRIPVTISubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
 ACT_SITE 273 273 By similarity.
 ACT_SITE 332 332 By similarity.
 ACT_SITE 355 355 By similarity.
 METAL 395 395 Calcium (By similarity).
 METAL 397 397 Calcium (By similarity).
 METAL 444 444 Calcium (By similarity).
 METAL 449 449 Calcium (By similarity).  
Keyword
 Calcium; Complete proteome; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 705 AA 
Protein Sequence
SGVRITKVDW QHSENGAAHH TQDYPCPELV VRRGQLFSLT LDLNRALDSE EALIFTVETG 60
PHASEALHTK AIFQTAELEI GDTWTAAKEE QTENTITVSL SSPSNAVIGR YLLSARAASR 120
RKHSDRKLGQ FILLFNPWCP EDDVFLDSEE ERQEYVLNDS GIIFRGVEKH IRAQGWNYGQ 180
FEEDILNICL SILDRSPSHQ DDPATDVSHR HDPVYVTRII SAMVNSNNDR GVVQGQWQGK 240
YGGGTNPLNW RGSVAILQKW FKGKYKPVKY GQCWVFAGVM CTVLRCLGIA TRVVSNFNSA 300
HDTDGNLSVD KYVDSYGRTL EDLTEDSMWN FHVWNESWFA RQDLGSSYDG WQVLDATPQE 360
ESEGTFQCGP ASVTAIREGD VHLAHDGPFV FAEVNADYIT WLWHEDKRRE RVYSDTKKIG 420
RCISTKAVGS DSRVDITGLY KYPEGSRKER QVYGKALKKL LSVEAWGRRR RIRRASVRGI 480
WRDDLLEPVT KPSITGKFKV LEPPVLGQDL KLALCLTNLT TRAQRVRVNV SGATILYTRK 540
PVAEILRESH TMKLGPLEEK RIPVTISYSQ YKEDLTEDKK ILLAAMCLVS KGEKLLVEKD 600
ITLEDFITIK VLGPAVVGVT VAVEVLVINP LSESVKDCVL MVEGSGLLQG QLSVEVPSLK 660
PQERALIQFN ITPSKSGPRQ LQVDLVSSQF PDIKGFVIIH VATAK 705 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
 GO:0018149; P:peptide cross-linking; IEA:InterPro. 
Interpro
 IPR023608; Gln_gamma-glutamylTfrase_euk.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002931; Transglutaminase-like.
 IPR008958; Transglutaminase_C.
 IPR013808; Transglutaminase_CS.
 IPR001102; Transglutaminase_N. 
Pfam
 PF00927; Transglut_C
 PF01841; Transglut_core
 PF00868; Transglut_N 
SMART
 SM00460; TGc 
PROSITE
 PS00547; TRANSGLUTAMINASES 
PRINTS