CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040810
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ras-related protein Rab-24 
Protein Synonyms/Alias
  
Gene Name
 RAB24 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
75ERAKFWVKELRSLEEubiquitination[1, 2]
127QLFETSSKTGQSVDEubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 174 AA 
Protein Sequence
MAPISSLSLQ TIGAAFVAKV MSVGDRTVTL GIWDTAGSER YEAMSRIYYR GAKAAIVCYD 60
LTDSSSFERA KFWVKELRSL EEGCQIYLCG TKSDLLEEDR RRRRVDFHDV QDYADNIKAQ 120
LFETSSKTGQ SVDELFQKVA EDYVSVAAFQ VMTEDKGVDL GQKPNPYFYS CCHH 174 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase. 
Pfam
 PF00071; Ras 
SMART
  
PROSITE
  
PRINTS
 PR00449; RASTRNSFRMNG.