CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005764
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S6 
Protein Synonyms/Alias
  
Gene Name
 RpS6 
Gene Synonyms/Alias
 hen; l(1)air8; CG10944 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
143KRASKIRKLYNLSKEacetylation[1]
204KKRQIASKEASADYAacetylation[1]
212EASADYAKLLVQRKKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. 
Sequence Annotation
 MOD_RES 233 233 Phosphoserine.
 MOD_RES 235 235 Phosphoserine.
 MOD_RES 239 239 Phosphoserine.
 MOD_RES 242 242 Phosphoserine.
 MOD_RES 244 244 Phosphoserine.
 MOD_RES 245 245 Phosphoserine.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 248 AA 
Protein Sequence
MKLNVSYPAT GCQKLFEVVD EHKLRVFYEK RMGQVVEADI LGDEWKGYQL RIAGGNDKQG 60
FPMKQGVLTH GRVRLLLKKG HSCYRPRRTG ERKRKSVRGC IVDANMSVLA LVVLKKGEKD 120
IPGLTDTTIP RRLGPKRASK IRKLYNLSKE DDVRRFVVRR PLPAKDNKKA TSKAPKIQRL 180
ITPVVLQRKH RRIALKKKRQ IASKEASADY AKLLVQRKKE SKAKREEAKR RRSASIRESK 240
SSVSSDKK 248 
Gene Ontology
 GO:0005840; C:ribosome; IDA:FlyBase.
 GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
 GO:0051298; P:centrosome duplication; IMP:FlyBase.
 GO:0006955; P:immune response; TAS:FlyBase.
 GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR014401; Ribosomal_S6_euk.
 IPR001377; Ribosomal_S6e.
 IPR018282; Ribosomal_S6e_CS. 
Pfam
 PF01092; Ribosomal_S6e 
SMART
  
PROSITE
 PS00578; RIBOSOMAL_S6E 
PRINTS