CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028766
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear factor of activated T-cells c2 isoform IA-IIL-VIIa 
Protein Synonyms/Alias
 Nuclear factor of-activated T-cells, cytoplasmic 2 
Gene Name
 Nfatc2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
512NADIELRKGETDIGRacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 653 AA 
Protein Sequence
MQRPALRRPG PRQPLRTMGS ADREEPIAHK AISSPSGLAY PDDVLDYGLK PCNPLASLSG 60
EPPGRFGEPD SIGFQNFLSP VKPAGASGPS PRIEITPSHE LMQAGGALRG RDAGLSPEQP 120
ALALAGVAAS PRFTLPVPGY EGYREPLCLS PASSGSSASF ISDTFSPYTS PCVSPNNAGP 180
DDLCPQFQNI PAHYSPRTSP IMSPRTSLAE DSCLGRHSPV PRPASRSSSP GAKRRHSCAE 240
ALVAPLPAAS PQRSRSPSPQ PSPHVALQDD SIPAGYPPTA GSAVLMDALN TLATDSPCGI 300
PSKIWKTSPD PTPVSTAPSK AGLARHIYPT VEFLGPCEQE ERRNSAPESI LLVPPTWPKQ 360
LVPAIPICSI PVTASLPPLE WPLSNQSGSY ELRIEVQPKP HHRAHYETEG SRGAVKAPTG 420
GHPVVQLHGY MENKPLGLQI FIGTADERIL KPHAFYQVHR ITGKTVTTTS YEKIVGNTKV 480
LEIPLEPKNN MRATIDCAGI LKLRNADIEL RKGETDIGRK NTRVRLVFRV HVPEPSGRIV 540
SLQAASNPIE CSQRSAHELP MVERQDMDSC LVYGGQQMIL TGQNFTAESK VVFMEKTTGP 600
AGTCETRPLP ISLISADRLS PWLSRLQRNP PGSVFRCSVL LPAPGSSLVL LAL 653 
Gene Ontology
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0030529; C:ribonucleoprotein complex; IDA:MGI.
 GO:0005667; C:transcription factor complex; IPI:MGI.
 GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0001816; P:cytokine production; IDA:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. 
Interpro
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR008366; NFAT.
 IPR008967; p53-like_TF_DNA-bd.
 IPR011539; RHD. 
Pfam
 PF00554; RHD 
SMART
  
PROSITE
 PS50254; REL_2 
PRINTS
 PR01789; NUCFACTORATC.