CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045517
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Itgae 
Protein Synonyms/Alias
 RCG33209 
Gene Name
 Itgae 
Gene Synonyms/Alias
 rCG_33209 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
350NNTYRELKLIASDPKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1169 AA 
Protein Sequence
MKWFFHALLC VASLKPLGAF NVDVDWSWVT ALQPGAPSVL NSLLHQDPSN NQTCLLVARR 60
SSNRNSAVLY RCATSIIPDE IGCQPVEHIL MPKGRYQGVT LVRNHNGVLV CIQVQSRKPR 120
SLNSELTGAC SLLTPNLDLQ AQAYFSDLEG VLDLGASVNS GDYYGSKGGS TGEETKSARR 180
LRRQAVEEED EEEAGTEIAI VLDGSGSIEP SDFQKAKDFI STMMRNFYEK CFECNFALVQ 240
YGGVIQTEFD LLDSRDINAS LAKVQSIVQV KEVTKTASAM QHVLDNIFIP SRGSRKKALK 300
VMVVLTDGDI FRDPLNLTTV ISSSKMQGVV RFAIGVGNAF ENNNTYRELK LIASDPKAAH 360
TFKVTNYSAL DGLLSKLQQR IIHMEGTVGD TLQYQLAQTG FSAQILDKGQ VLLGTVGAFN 420
WSGGALLYNT QNGRGRFLNQ TAKEDFRAAQ YSYLGYSVAA LHKAHGVSYV AGAPRHKLRG 480
AVFELQKEDG EETFMRRIEG EQMGSYFGSV LCPVDINMDG ITDFLLVAAP FYHIRGEEGR 540
VYVYRVHEQD APFSLVYTLS GYPGLTSSRF GFAMAAVGDI NQDKFTDVAI GAPLEGFGAG 600
DGASYGSVYI YNGHSGGLHA SPSQQIRASS VALGLYYFGM SVSGGLDFSG DDLADITVGS 660
QDVAVVLRSR PVVDLTVSMT FTPDALPMAF KDKMDVELCF KVDSSAVPSE PGLRGMSLNF 720
TVDVDVTKQK QRLQCADRSC CQSCLMKWSG GSSLCEHFGL ISTEEELCED DCFSNITIKV 780
SYEFQTSEER RNHPNPILDH YKEPSAIFQL PYEKDCKNKV FCIAEIQLTT AISQQDLVVG 840
ITKEVTMNIS LTNSGEDSYM TNMALNYPRN LQFKKIQKPL SPDIQCDDPK PVASVLVMNC 900
KIGHPILKRS SVNVSVTWQL EESIFPNRTA DITVTISNSN EKSLARETHS LQFRHAFIAV 960
LSRPSVMYMN TSQSSSDHKE FFFNVHGENH FGAVFQLQIC VPITLRDLQI IRVKHLTKTQ 1020
AHTECTQSQE PTCGSDPVQN VEEWHSVICA ITSNKENVTV AAEISMGHTK QLLRDISELQ 1080
ILGEISFNKS LYEGLNAENH RTKITVIFLK EEKPHSLPLI IGSSIGGLLV LVVIIAILFK 1140
CGFFKRKYKQ LNLESVRKAQ LKSDSLLED 1169 
Gene Ontology
 GO:0008305; C:integrin complex; IEA:InterPro.
 GO:0007155; P:cell adhesion; TAS:RGD.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. 
Interpro
 IPR013517; FG-GAP.
 IPR013519; Int_alpha_beta-p.
 IPR000413; Integrin_alpha.
 IPR013649; Integrin_alpha-2.
 IPR018184; Integrin_alpha_C_CS.
 IPR002035; VWF_A. 
Pfam
 PF01839; FG-GAP
 PF00357; Integrin_alpha
 PF08441; Integrin_alpha2
 PF00092; VWA 
SMART
 SM00191; Int_alpha
 SM00327; VWA 
PROSITE
 PS51470; FG_GAP
 PS00242; INTEGRIN_ALPHA
 PS50234; VWFA 
PRINTS
 PR01185; INTEGRINA.