CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020489
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Malignant T-cell-amplified sequence 2 
Protein Synonyms/Alias
 MCT-2; Multiple copies T-cell malignancies 2 
Gene Name
 Mcts2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
51MPKKDPVKIVRCHEHacetylation[1]
87PTLRLLHKYPFILPHacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
 DOMAIN 92 171 PUA.
 MOD_RES 81 81 Phosphothreonine (By similarity).
 MOD_RES 118 118 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MFKKFDEKES VSNCIQLKTS VIKGIKSQLT EQFPGIEPWL NQIMPKKDPV KIVRCHEHME 60
ILTVNGELLF FRQRKGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG 120
AKLYTAAVDT IVAVMAEGKE HALCVGVMKM AAADIEKINK GIGIENIHYL NDGLWHMKTY 180
K 181 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR002478; PUA.
 IPR015947; PUA-like_domain.
 IPR016437; Transl_RNA-bd_prd.
 IPR004521; Uncharacterised_CHP00451. 
Pfam
 PF01472; PUA 
SMART
 SM00359; PUA 
PROSITE
 PS50890; PUA 
PRINTS