CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006123
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative prephenate dehydratase 
Protein Synonyms/Alias
 PDT; Phenylalanine-requiring protein 2 
Gene Name
 PHA2 
Gene Synonyms/Alias
 YNL316C; N0351 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
212IEHSINDKLGNTTRFacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
  
Sequence Annotation
 DOMAIN 7 224 Prephenate dehydratase.
 DOMAIN 244 322 ACT.  
Keyword
 Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; Cytoplasm; Lyase; Phenylalanine biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
MASKTLRVLF LGPKGTYSHQ AALQQFQSTS DVEYLPAASI PQCFNQLEND TSIDYSVVPL 60
ENSTNGQVVF SYDLLRDRMI KKALSLPAPA DTNRITPDIE VIAEQYVPIT HCLISPIQLP 120
NGIASLGNFE EVIIHSHPQV WGQVECYLRS MAEKFPQVTF IRLDCSSTSE SVNQCIRSST 180
ADCDNILHLA IASETAAQLH KAYIIEHSIN DKLGNTTRFL VLKRRENAGD NEVEDTGLLR 240
VNLLTFTTRQ DDPGSLVDVL NILKIHSLNM CSINSRPFHL DEHDRNWRYL FFIEYYTEKN 300
TPKNKEKFYE DISDKSKQWC LWGTFPRNER YYHK 334 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0004664; F:prephenate dehydratase activity; IMP:SGD.
 GO:0009094; P:L-phenylalanine biosynthetic process; IMP:SGD. 
Interpro
 IPR001086; Preph_deHydtase. 
Pfam
 PF00800; PDT 
SMART
  
PROSITE
 PS51671; ACT
 PS00857; PREPHENATE_DEHYDR_1
 PS00858; PREPHENATE_DEHYDR_2
 PS51171; PREPHENATE_DEHYDR_3 
PRINTS