| Tag | Content |
|---|
| CPLM ID | CPLM-013616 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GPI ethanolamine phosphate transferase 2 |
Protein Synonyms/Alias | GPI7 homolog; hGPI7; Phosphatidylinositol-glycan biosynthesis class G protein; PIG-G |
Gene Name | PIGG |
Gene Synonyms/Alias | GPI7; UNQ1930/PRO4405 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 371 | ENVPSYEKDPGFEQF | ubiquitination | [1] | | 379 | DPGFEQFKMSERLHG | ubiquitination | [1] | | 627 | CDVLERDKGHGSPST | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. |
Sequence Annotation | CARBOHYD 194 194 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycoprotein; GPI-anchor biosynthesis; Membrane; Polymorphism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 983 AA |
Protein Sequence | MRLGSGTFAT CCVAIEVLGI AVFLRGFFPA PVRSSARAEH GAEPPAPEPS AGASSNWTTL 60
PPPLFSKVVI VLIDALRDDF VFGSKGVKFM PYTTYLVEKG ASHSFVAEAK PPTVTMPRIK 120
ALMTGSLPGF VDVIRNLNSP ALLEDSVIRQ AKAAGKRIVF YGDETWVKLF PKHFVEYDGT 180
TSFFVSDYTE VDNNVTRHLD KVLKRGDWDI LILHYLGLDH IGHISGPNSP LIGQKLSEMD 240
SVLMKIHTSL QSKERETPLP NLLVLCGDHG MSETGSHGAS STEEVNTPLI LISSAFERKP 300
GDIRHPKHVQ QTDVAATLAI ALGLPIPKDS VGSLLFPVVE GRPMREQLRF LHLNTVQLSK 360
LLQENVPSYE KDPGFEQFKM SERLHGNWIR LYLEEKHSEV LFNLGSKVLR QYLDALKTLS 420
LSLSAQVAQY DIYSMMVLTL LLLSVPQALR RKAELEVPLS SPGFSLLFYL VILVLSAVHV 480
IVCTSAESSC YFCGLSWLAA GGVMVLASAL LCVIVSVLTN VLVGGNTPRK NPMHPSSRWS 540
ELDLLILLGT AGHVLSLGAS SFVEEEHQTW YFLVNTLCLA LSQETYRNYF LGDDGEPPCG 600
LCVEQGHDGA TAAWQDGPGC DVLERDKGHG SPSTSEVLRG REKWMVLASP WLILACCRLL 660
RSLNQTGVQW AHRPDLGHWL TSSDHKAELS VLAALSLLVV FVLVQRGCSP VSKAALALGL 720
LGVYCYRAAI GSVRFPWRPD SKDISKGIIE ARFVYVFVLG ILFTGTKDLL KSQVIAADFK 780
LKTVGLWEIY SGLVLLAALL FRPHNLPVLA FSLLIQTLMT KFIWKPLRHD AAEITVMHYW 840
FGQAFFYFQG NSNNIATVDI SAGFVGLDTY VEIPAVLLTA FGTYAGPVLW ASHLVHFLSS 900
ETRSGSALSH ACFCYALICS IPVFTYIVLV TSLRYHLFIW SVFSPKLLYE GMHLLITAAV 960
CVFFTAMDQT RLTQS 975 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0051267; F:CP2 mannose-ethanolamine phosphotransferase activity; IDA:MGI. GO:0006501; P:C-terminal protein lipidation; TAS:Reactome. GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |