| Tag | Content |
|---|
| CPLM ID | CPLM-010816 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA-directed RNA polymerase I subunit RPA49 |
Protein Synonyms/Alias | A49; DNA-directed RNA polymerase I 49 kDa polypeptide |
Gene Name | RPA49 |
Gene Synonyms/Alias | RRN13; YNL248C; N0880 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 92 | KKSIQLYKAPVLVSK | acetylation | [1] | | 99 | KAPVLVSKVVSKSSK | acetylation | [1] | | 170 | DSVRTASKDLPTRAQ | acetylation | [1] | | 241 | FPYQNNSKYVAKKLD | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. |
Sequence Annotation | MOD_RES 34 34 Phosphoserine.
MOD_RES 151 151 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; DNA-directed RNA polymerase; Nucleotidyltransferase; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 415 AA |
Protein Sequence | MSVKRSVSEI EIESVQDQPS VAVGSFFKGF RAPSDTTFDL YKKKKSEKDE FVLHGENERL 60
EYEGYTDSSS QASNQYVVGL FNPEKKSIQL YKAPVLVSKV VSKSSKNLRG PKIKSKSDTR 120
PSALRNALGE AFGTKKAKKA IADLERNRID SDKLTDSAID IVDSVRTASK DLPTRAQLDE 180
ITSNDRPTPL ANIDATDVEQ IYPIESIIPK KELQFIRVSS ILKEADKEKK LELFPYQNNS 240
KYVAKKLDSL TQPSQMTKLQ LLYYLSLLLG VYENRRVNNK TKLLERLNSP PEILVDGILS 300
RFTVIKPGQF GRSKDRSYFI DPQNEDKILC YILAIIMHLD NFIVEITPLA HELNLKPSKV 360
VSLFRVLGAI VKGATVAQAE AFGIPKSTAA SYKIATMKVP FKLPEMTRRG RGPRR 415 |
Gene Ontology | GO:0005736; C:DNA-directed RNA polymerase I complex; IDA:SGD. GO:0003677; F:DNA binding; IEA:InterPro. GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW. GO:0008361; P:regulation of cell size; IMP:SGD. GO:0006362; P:transcription elongation from RNA polymerase I promoter; IDA:SGD. GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |