| Tag | Content |
|---|
| CPLM ID | CPLM-021737 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium-coupled neutral amino acid transporter 3 |
Protein Synonyms/Alias | N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 |
Gene Name | Slc38a3 |
Gene Synonyms/Alias | Snat3 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 54 | FLQQSSSKEPHFTDF | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Sodium-dependent amino acid/proton antiporter. Mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. Also recognizes histidine and asparagine. May mediate amino acid transport in either direction under physiological conditions. May play a role in nitrogen metabolism and synaptic transmission. |
Sequence Annotation | MOD_RES 51 51 Phosphoserine (By similarity).
MOD_RES 53 53 Phosphoserine (By similarity).
CARBOHYD 73 73 N-linked (GlcNAc...) (Potential).
CARBOHYD 247 247 N-linked (GlcNAc...) (Potential).
CARBOHYD 251 251 N-linked (GlcNAc...) (Potential).
CARBOHYD 323 323 N-linked (GlcNAc...) (Potential). |
Keyword | Amino-acid transport; Antiport; Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Sodium; Sodium transport; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 504 AA |
Protein Sequence | MEIPRQTEMV ELVPNGKHLE GLLPVGMPTA DTQRAEDAQH CGEGKGFLQQ SSSKEPHFTD 60
FEGKTSFGMS VFNLSNAIMG SGILGLAYAM ANTGIILFLF LLTAVALLSS YSIHLLLKSS 120
GIVGIRAYEQ LGYRAFGTPG KLAAALAITL QNIGAMSSYL YIIKSELPLV IQTFLNLEKP 180
TPVWYMDGNY LVILVSVIII LPLALMRQLG YLGYSSGFSL SCMVFFLIAV IYKKFQVPCP 240
LAHNLVNATG NFSHMVVVEE KSQLQSEPDT AEAFCTPSYF TLNSQTAYTI PIMAFAFVCH 300
PEVLPIYTEL KDPSKRKMQH ISNLSIAVMY VMYFLAALFG YLTFYDGVES ELLHTYSKVD 360
PFDVLILCVR VAVLIAVTLT VPIVLFPVRR AIQQMLFQNQ EFSWLRHVLI ATGLLTCINL 420
LVIFAPNILG IFGIIGATSA PCLIFIFPAI FYFRIMPTEK EPVRSTPKIL ALCFAAVGFL 480
LMTMSLSFII TDWVSGTSQH GGNH 504 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. GO:0015297; F:antiporter activity; IEA:UniProtKB-KW. GO:0015182; F:L-asparagine transmembrane transporter activity; IDA:UniProtKB. GO:0015186; F:L-glutamine transmembrane transporter activity; IDA:UniProtKB. GO:0005290; F:L-histidine transmembrane transporter activity; IDA:UniProtKB. GO:0015293; F:symporter activity; IEA:UniProtKB-KW. GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |