| Tag | Content |
|---|
| CPLM ID | CPLM-011221 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-splicing factor RSE1 |
Protein Synonyms/Alias | RNA splicing and ER to Golgi transport factor 1; Spliceosome-associated protein 130 |
Gene Name | RSE1 |
Gene Synonyms/Alias | SAP130; YML049C; YM9827.03C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1165 | ELSNGAIKYPLDVIT | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in G2/M transition (By similarity). Required for pre-mRNA splicing and endoplasmic reticulum (ER) to Golgi secretion pathway. U2 snRNPs associated protein required for the pre-spliceosome assembly. The involvement in ER to Golgi secretion is probably indirect and due to the splicing of the pre-mRNA coding for SAR1, a small GTP-binding protein required for COPII vesicle formation from the ER. |
Sequence Annotation | |
Keyword | Cell cycle; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1361 AA |
Protein Sequence | MWGGGKMAVV SLSPHTAKMR KLFGQASTTM AYDGLKREAE RRTRSDHNIT MVAKDDELYL 60
YHLTLKKQTN FVHSCIGHFV DLEAGSKREQ SQLCVATETH LELYDTADGE LKLIAKFQNL 120
FATITSMKSL DLPHSGSRAK ASNWPTFLAL TSDSGNLSIV QIIMHAGALR LKTLVNQPLT 180
RTTLRRVSPI SYMEIDPNGR CIILSSVEQN KLCFLVDYAQ KLRISSPLEI IRPHMVTLDM 240
AVVDVNFNNP CFVTLEIDNA ATQLSVHLIF YVLELGLNHI VKKADYLVNP SANFVLSLPD 300
LSRYNITTSL SDNNYDADYD TLFNPFVVIG FENHILVKDM NGFFSLKVEI PKRSITNSRH 360
KNVTIISGIV QKLKNDFFVL LQSNHGDLFK LTVSPDTNDR NRPLVQLSYF DTIQNSHQLH 420
IFKNGYLFAL SEMNNNFLFQ FEKLGVEKND FSNVLTSKDP NKSLVFEPSI KLQNLSILSQ 480
QLNLNPSIKS QIVSDSPLSI ATKHFTNNKI ITLTNAVNYS NLISTSLPPN ATKLWLIPDP 540
ATTGDNNTLL FITFPKKTMI LQIDNESMEE LTPDEATRSA FKLSQDTTIH TCLMGSHSII 600
QVCTAELRHI VPTGKSRYSN KLTWVPPAGI RIVCATSSKT QLIISLSNYE LVYFKIDVSS 660
DSLIELTTHP ELDTMPSKVA IVQDTQHADL LAIADNEGMI KIMSLKDQKE DFLTVISLQL 720
VSEKISDMIM VRDSSIGQLN LHVGLENGVY MKFHIGDVDG SFTDIKRRFL GLKPVSLSYL 780
REISVSLNNE EEEEEEEDDD DEKEEEEINS SGAKWMSCVV CHSSSTWVSY TWKNVWTIRQ 840
LKDQNMLSCS KFVNADVAIN GVCSISSSGR LNIGRVSNFP TLDNWFHVHE SSVNKQENGG 900
GDESNEEEED EMEEEMEMLQ ISTFRPRTIL SFPNNPKSIL FIDNHSGKKQ CRISLQIDGE 960
CLKFGSSDHL YKILDDIDCV SAAIIDFTRQ ADHLIICAGD KRLLTYKILV NKDKLSFDIE 1020
LLHQTEIISP IHAMLKFKNF LLTAMGSTIV LYGLGKKQLL RRSVTQTPVS ITKIVSMHQW 1080
NYERLAVGDI HESVTLFIWD PAGNVFIPYV DDSVKRHVTV LKFLDEATVI GADRYGNAWT 1140
LRSPPECEKI MSNHDPSELS NGAIKYPLDV ITLQQKLPNT YDCKFKFQLL NHFFVNDIIT 1200
DFHILDSLSN SDRPGCIYMG LQGTVGCFIP LLSKGNVFMM GNIENIMAEA DDTFYLDYES 1260
RKKNNNMRKE DDEEESGSVV LQGRHGIEDE IICEGSCSIL GRDHQEYRSY YAPVRKVIDG 1320
DLCENFLRLS LNEQEFLAKN LKSVQVEDII QTINEVRTNY M 1361 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |