UniProt Accession

 PDLI1_RAT; P52944; Q6IN45 

Genbank Protein ID

 U23769; BC072465 

Genbank Nucleotide ID

 AAA92046.1; AAH72465.1 

Protein Name

 PDZ and LIM domain protein 1 

Protein Synonyms/Alias

 C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36 

Gene Name

 Pdlim1 

Gene Synonyms/Alias

 Clim1; Clp36 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
22	GFRLVGGKDFEQPLA	acetylation	[1]
98	PLVTEEGKRHPYKMN	acetylation	[1]
103	EGKRHPYKMNLASEP	acetylation	[1]
231	DGKGDPNKPSGFRSV	acetylation	[1]
307	GDQIYCEKHARERVT	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). 

Sequence Annotation

 DOMAIN 3 85 PDZ.
 DOMAIN 256 315 LIM zinc-binding.
 METAL 258 258 Zinc 1 (By similarity).
 METAL 261 261 Zinc 1 (By similarity).
 METAL 278 278 Zinc 1 (By similarity).
 METAL 281 281 Zinc 1 (By similarity).
 METAL 284 284 Zinc 2 (By similarity).
 METAL 287 287 Zinc 2 (By similarity).
 METAL 305 305 Zinc 2 (By similarity).
 METAL 308 308 Zinc 2 (By similarity).
 MOD_RES 2 2 N-acetylthreonine (By similarity).
 MOD_RES 90 90 Phosphoserine (By similarity).
 MOD_RES 130 130 Phosphoserine (By similarity).
 MOD_RES 142 142 Phosphotyrosine (By similarity).
 MOD_RES 319 319 Phosphotyrosine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; LIM domain; Metal-binding; Phosphoprotein; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 327 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEP:RGD. 

Interpro

 IPR001478; PDZ.
 IPR001781; Znf_LIM. 

Pfam

 PF00412; LIM
 PF00595; PDZ 

SMART

 SM00132; LIM
 SM00228; PDZ 

PROSITE

 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2
 PS50106; PDZ 

PRINTS