CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030387
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dis3 protein 
Protein Synonyms/Alias
 Protein Dis3 
Gene Name
 Dis3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
377HLFTPADKRIPRIRIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 957 AA 
Protein Sequence
MLKSKTFLKK TRAGGVVKIV REHYLRDDIG CGTPACSACG AAHAGPALEL QPRDQASSLC 60
PWPHYLLPDT NVLLHQIDVL EDPAIRNVIV LQTVLQEVRN RSAPIYKRIR DVTNNQEKHF 120
YTFTNEHHKE TYIEQEQGEN ANDRNDRAIR VAAKWYNEHL KMSAENQLQV ILITNDKKNK 180
EKAAEEGIPA FTCEEYVKSL TANPELIDRL ACLSDEMNEI ESGKIIFSEH LPLSKLQQGI 240
KSGSYLQGTF RASRENYLEA TVWIHGDKED EKEILIQGLK HLNRAIHEDI VAVELLPKSQ 300
WVAPSSVVLH DEGQNEDDVE KDEERELLLK TAVSEKMLRP TGRVVGIIKR NWRPYCGMLS 360
KSDIKESRRH LFTPADKRIP RIRIETRQAS ALEGRRIIVA IDGWPRNSRY PNGHFVKNLG 420
DVGEKETETE VLLLEHDVPH QPFSQAVLSF LPKMPWSITE EDMKNREDLR HLCVCSVDPP 480
GCTDIDDALH CRELSNGNLE VGVHIADVSH FIRPGNALDQ ESARRGTTVY LCEKRIDMVP 540
ELLSSNLCSL RSNVDRLAFS CIWEMNHNAE ILKTRFTKSV INSKASLTYA EAQMRIDSAA 600
MNDDITTSLR GLNKLAKILK RGRIEKGALT LSSPEIRFHM DSETHDPIDL QTKELRETNS 660
MVEEFMLLAN ISVAKKIHEE FSEHALLRKH PAPPPSNYEV LVKAAKSKNL EIRTDTAKSL 720
ADSLDRAECP DFPYLNTLLR ILATRCMMQA VYFCSGMDSD FHHYGLASPI YTHFTSPIRR 780
YADIIVHRLL AVAIGADCTY PELTDKHKLS DICKNLNFRH KMAQYAQRAS VAFHTQLFFK 840
SKGIVSEEAY ILFVRKNAIV VLIPKYGLEG TVFFEEKDKP KPRLTYDDEI PSLRIEGTVF 900
HVFDKVKVKI TLDSSNLQHQ KIRMALVEPQ IPGINMPPDV SDMDLNGPGG KKRKLEK 957 
Gene Ontology
 GO:0000176; C:nuclear exosome (RNase complex); IEA:Compara.
 GO:0005654; C:nucleoplasm; IEA:Compara.
 GO:0000175; F:3'-5'-exoribonuclease activity; IEA:Compara.
 GO:0004519; F:endonuclease activity; IEA:Compara.
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:Compara.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0071034; P:CUT catabolic process; IEA:Compara.
 GO:0016075; P:rRNA catabolic process; IEA:Compara. 
Interpro
 IPR002716; PIN_dom.
 IPR006596; PINc_nuc-bd.
 IPR001900; RNase_II/R.
 IPR022966; RNase_II/R_CS. 
Pfam
 PF13638; PIN_4
 PF00773; RNB 
SMART
 SM00670; PINc
 SM00955; RNB 
PROSITE
 PS01175; RIBONUCLEASE_II 
PRINTS