CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018969
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Loss of heterozygosity 12 chromosomal region 1 protein 
Protein Synonyms/Alias
  
Gene Name
 LOH12CR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
30SPAKHRAKMDDIVVVubiquitination[1]
67PTFQPLLKGLLSGQTubiquitination[2]
80QTSPTNAKLEKLDSQubiquitination[1, 3]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 MOD_RES 75 75 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 196 AA 
Protein Sequence
MGSEQSSEAE SRPNDLNSSV TPSPAKHRAK MDDIVVVAQG SQASRNVSND PDVIKLQEIP 60
TFQPLLKGLL SGQTSPTNAK LEKLDSQQVL QLCLRYQDHL HQCAEAVAFD QNALVKRIKE 120
MDLSVETLFS FMQERQKRYA KYAEQIQKVN EMSAILRRIQ MGIDQTVPLL DRLNSMLPEG 180
ERLEPFSMKP DRELRL 196 
Gene Ontology
  
Interpro
 IPR018780; Tumour_suppressor_LOH1CR12. 
Pfam
 PF10158; LOH1CR12 
SMART
  
PROSITE
  
PRINTS