CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 H-2 class I histocompatibility antigen, K-K alpha chain 
Protein Synonyms/Alias
  
Gene Name
 H2-K1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
214EWLRRYLKNGNATLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MVPCTLLLLL AAALAPTQTR AARAAARGLV RWSGSHRAPP PGPHSLRYFV TAVSRPGLGE 60
PRYMEVGYVD DTEFVRFDSD AENPRYEPRA RWMEQEGPEY WERETQKAKG NEQSFRVDLR 120
TLLGYYNQSK GGSHTIQVIS GCEVGSDGRL LRGYQQYAYD GCDYIALNED LKTWTAADMA 180
ALITKHKWEQ AGEAERLRAY LEGTCVEWLR RYLKNGNATL LRTDSPKAHV THHSRPEDKV 240
TLRCWALGFY PADITLTWQL NGEELIQDME LVETRPAGDG TFQKWASVV 289 
Gene Ontology
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0042612; C:MHC class I protein complex; IEA:InterPro.
 GO:0042605; F:peptide antigen binding; IDA:MGI.
 GO:0002485; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; IDA:MGI.
 GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; IDA:MGI.
 GO:0042742; P:defense response to bacterium; IDA:MGI.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0048839; P:inner ear development; IDA:MGI.
 GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:MGI. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2. 
Pfam
 PF07654; C1-set
 PF00129; MHC_I 
SMART
  
PROSITE
 PS50835; IG_LIKE 
PRINTS
 PR01638; MHCCLASSI.