UniProt Accession

 NHOA_ECOLI; P77567 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74545.1; BAA15100.1 

Protein Name

 N-hydroxyarylamine O-acetyltransferase 

Protein Synonyms/Alias

 Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT102 

Gene Name

 nhoA 

Gene Synonyms/Alias

 yddI; b1463; JW1458 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
59	DNQSPEEKLVIARRG	acetylation	[1]
214	RHLPDGGKLTLTNFH	acetylation	[1, 2]
281	DTHPEAGK*******	acetylation	[2]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase.
 Zhang Q, Gu J, Gong P, Wang X, Tu S, Bi L, Yu Z, Zhang Z, Cui Z, Wei H, Tao S, Zhang X.
 FEBS J. 2013 May;280(9):1966-79. [PMID: 23452042] 

Functional Description

  

Sequence Annotation

 ACT_SITE 69 69 Acyl-thioester intermediate (By
 ACT_SITE 107 107 By similarity.
 ACT_SITE 122 122 By similarity.  

Keyword

 Acyltransferase; Complete proteome; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 281 AA 

Protein Sequence

Gene Ontology

 GO:0046990; F:N-hydroxyarylamine O-acetyltransferase activity; IEA:EC. 

Interpro

 IPR001447; Arylamine_N-AcTrfase. 

Pfam

 PF00797; Acetyltransf_2 

SMART

  

PROSITE

  

PRINTS

 PR01543; ANATRNSFRASE.